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Protective Effects of Corni Fructus against Advanced Glycation Endproducts and Radical Scavenging
المؤلفون المشاركون
Yokozawa, Takako
Park, Jong Cheol
Tanaka, Takashi
Kim, Hyun Young
Park, Chan Hum
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-05-09
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
We investigated the inhibition of advanced glycation endproduct (AGE) activity using the fluorescence characteristics of fractions and compounds from Corni Fructus.
Corni Fructus extract and its iridoid glycoside components showed low inhibitory activities as well as the AGE inhibitor aminoguanidine.
However, a low molecular weight polyphenol, 7-O-galloyl-D-sedoheptulose, and an antioxidant, trolox, showed high inhibitory activities compared with aminoguanidine under reactive conditions.
The AGE-inhibiting activity of polyphenolic fractions of Corni Fructus ranged from a level comparable to Corni Fructus extract to the higher level of 7-O-galloyl-D-sedoheptulose.
As well as the results of AGE-inhibiting activity, Corni Fructus extract and iridoid components showed low or no 1,1-diphenyl-2-pycrylhydrazyl (DPPH) radical-scavenging activities, whereas 7-O-galloyl-D-sedoheptulose showed a level comparable to trolox.
Polyphenolic fractions of Corni Fructus quenched DPPH radicals in a concentration-dependent manner.
Some fractions exerted a higher DPPH radical-scavenging activity compared with trolox and 7-O-galloyl-D-sedoheptulose.
The DPPH radical-scavenging activity was significantly correlated with the AGE-inhibiting activity.
These results suggest that polyphenolic fractions of Corni Fructus inhibited AGE formation by antioxidant activity including free radical scavenging.
The strong DPPH radical-scavenging and AGE-inhibiting fractions included ellagitannins and polymeric proanthocyanidins.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Park, Chan Hum& Tanaka, Takashi& Kim, Hyun Young& Park, Jong Cheol& Yokozawa, Takako. 2012. Protective Effects of Corni Fructus against Advanced Glycation Endproducts and Radical Scavenging. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1028304
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Park, Chan Hum…[et al.]. Protective Effects of Corni Fructus against Advanced Glycation Endproducts and Radical Scavenging. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-1028304
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Park, Chan Hum& Tanaka, Takashi& Kim, Hyun Young& Park, Jong Cheol& Yokozawa, Takako. Protective Effects of Corni Fructus against Advanced Glycation Endproducts and Radical Scavenging. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1028304
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1028304
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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