Therapeutic Effects of Acupuncture through Enhancement of Functional Angiogenesis and Granulogenesis in Rat Wound Healing
المؤلفون المشاركون
Maeng, Lee-So
Jung, Yu Jin
Chang, Woo Chul
Park, Moon-Seo
Shin, Hak Soo
Lee, Jisoo
Chung, Young-An
Park, Sang In
Sunwoo, Yun-Young
Han, Young-Min
Chung, Yong-An
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-10
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Acupuncture regulates inflammation process and growth factors by increasing blood circulation in affected areas.
In this study, we examined whether acupuncture has an effect on wound healing in injured rat.
Rats were assigned randomly into two groups: control group and acupuncture group.
Acupuncture treatment was carried out at 8 sites around the wounded area.
We analyzed the wound area, inflammatory cytokines, proliferation of resident cells, and angiogenesis and induction of extracelluar matrix remodeling.
At 7 days after-wounding the wound size in acupuncture-treat group was decreased more significantly compared to control group.
In addition, the protein levels of proinflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) were significantly decreased compared to the control at 2 and 7 days post-wounding.
Also, we analyzed newly generated cells by performing immunostaining for PCNA and using several phenotype markers such as CD-31, α-SMA, and collagen type I.
In acupuncture-treated group, PCNA-positive cell was increased and PCNA labeled CD-31-positive vessels, α-SMA- and collagen type I-positive fibroblastic cells, were increased compared to the control group at 7 days post-wounding.
These results suggest that acupuncture may improve wound healing through decreasing pro-inflammatory response, increasing cell proliferation and angiogenesis, and inducing extracellular matrix remodeling.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Park, Sang In& Sunwoo, Yun-Young& Jung, Yu Jin& Chang, Woo Chul& Park, Moon-Seo& Chung, Young-An…[et al.]. 2012. Therapeutic Effects of Acupuncture through Enhancement of Functional Angiogenesis and Granulogenesis in Rat Wound Healing. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-1028326
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Park, Sang In…[et al.]. Therapeutic Effects of Acupuncture through Enhancement of Functional Angiogenesis and Granulogenesis in Rat Wound Healing. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-1028326
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Park, Sang In& Sunwoo, Yun-Young& Jung, Yu Jin& Chang, Woo Chul& Park, Moon-Seo& Chung, Young-An…[et al.]. Therapeutic Effects of Acupuncture through Enhancement of Functional Angiogenesis and Granulogenesis in Rat Wound Healing. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-1028326
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1028326
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر