Validation Study of Kim's Sham Needle by Measuring Facial Temperature: An N-of-1 Randomized Double-Blind Placebo-Controlled Clinical Trial

الملخص EN

Introduction.

In 2008, Kim's sham needle was developed to improve the quality of double-blinded studies.

The aim of this study is to validate Kim's sham needle by measuring facial temperature.

Methods.

We designed “N-of-1” trials involving 7 smokers.

One session was composed of 2 stimulations separated by a 2 h washout period.

Six sessions were applied daily for all subjects.

Infrared thermal imaging was used to examine the effects of acupuncture (HT8, KI2) on facial temperature following smoking-induced decrease.

Results.

All subjects demonstrated decreased temperatures after sham needle treatment, but 5 of the 7 subjects showed increased temperatures after real needle treatment.

6 of the 7 subjects showed a significant difference (P<0.05) between treatments with real and sham needles.

Thus, the physiological stimulation of Kim's sham needle is different from that of a real needle, suggesting that Kim's sham needle is a potential inactive control intervention.