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Epimedium koreanum Extract and Its Constituent Icariin Improve Motor Dysfunction in Spinal Cord Injury
المؤلفون المشاركون
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-23
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Although cell transplantation strategies for spinal cord injury (SCI) using sources such as iPS cells and neural stem cells are focused as expectative therapies for SCI, the possibility of medication as more accessible and practical way should not be given up.
We, therefore, aimed to develop medical sources for SCI.
In this paper, we evaluated effects of a famous tonic herb, Epimedium koreanum, on motor dysfunction in spinal cord injury (SCI).
The spinal cord was injured by contusion after laminectomy at T10 level.
Oral administration of the methanol extract of E.
koreanum significantly enhanced hindlimb function in SCI mice by short period treatment (for initial 3 days) and chronic treatment (21 days), although chronic treatment recovered the function more potently.
Since it is well known that icariin is the major constituent in E.
koreanum, icariin was administered orally to SCI mice for initial 3 days.
Motor dysfunction was ameliorated by icariin treatment similarly to the methanol extract of E.
koreanum.
This paper is the first report to indicate E.
koreanum is effective for recovery of motor function in SCI, and at least icariin is an active constituent.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tohda, Chihiro& Nagata, Aiko. 2012. Epimedium koreanum Extract and Its Constituent Icariin Improve Motor Dysfunction in Spinal Cord Injury. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1028509
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tohda, Chihiro& Nagata, Aiko. Epimedium koreanum Extract and Its Constituent Icariin Improve Motor Dysfunction in Spinal Cord Injury. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-1028509
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tohda, Chihiro& Nagata, Aiko. Epimedium koreanum Extract and Its Constituent Icariin Improve Motor Dysfunction in Spinal Cord Injury. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1028509
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1028509
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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