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The Tibetan Uterotonic Zhi Byed 11: Mechanisms of Action, Efficacy, and Historical Use for Postpartum Hemorrhage
المؤلفون المشاركون
Miller, Suellen
Coelius, Rebecca Lynn
Stenson, Amy
Cuomu, Mingji
Tudor, Carrie
Morris, Jessica
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-07-21
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
To explore evidence for the traditional Tibetan medicine, Zhi Byed 11 (ZB11), for use as a uterotonic.
Methods.
The eleven ingredients in ZB11 were chemically analyzed by mass spectroscopy.
A review was conducted of Western allopathic literature for scientific studies on ZB11’s individual components.
Literature from Tibetan and other traditional paradigms were reviewed.
Results.
Potential mechanisms of action for ZB11 as a uterotonic include laxative effects, a dose-dependant increase in smooth muscle tissue peristalsis that may also affect the uterus smooth muscle, and chemical components that are prostaglandin precursors and/or increase prostaglandin synthesis.
A recent RCT demonstrated comparable efficacy to misoprostol in reducing severe postpartum hemorrhage (PPH) (>1000 mL) and greater effect than placebo.
Historical and anecdotal evidence for ZB11 and its ingredients for childbirth provide further support.
Discussion.
ZB11 and its ingredients are candidates for potentially effective uterotonics, especially in low-resource settings.
Further research is warranted to understand the mechanisms of action and synergy between ingredients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Coelius, Rebecca Lynn& Stenson, Amy& Morris, Jessica& Cuomu, Mingji& Tudor, Carrie& Miller, Suellen. 2011. The Tibetan Uterotonic Zhi Byed 11: Mechanisms of Action, Efficacy, and Historical Use for Postpartum Hemorrhage. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-1028542
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Coelius, Rebecca Lynn…[et al.]. The Tibetan Uterotonic Zhi Byed 11: Mechanisms of Action, Efficacy, and Historical Use for Postpartum Hemorrhage. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-1028542
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Coelius, Rebecca Lynn& Stenson, Amy& Morris, Jessica& Cuomu, Mingji& Tudor, Carrie& Miller, Suellen. The Tibetan Uterotonic Zhi Byed 11: Mechanisms of Action, Efficacy, and Historical Use for Postpartum Hemorrhage. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-1028542
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1028542
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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