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The Effects of Cosmos caudatus on Structural Bone Histomorphometry in Ovariectomized Rats
المؤلفون المشاركون
Shuid, Ahmad Nazrun
Othman, Faizah
Ima-Nirwana, Soelaiman
Gwee Sian Khee, Sharon
Babji, Abdul Salam
Mohamed, Norazlina
Muhammad, Norliza
Haji Suhaimi, Farihah
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-08
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Osteoporosis is considered a serious debilitating disease.
Cosmos caudatus (ulam raja), a plant containing antioxidant compounds and minerals, may be used to treat and prevent osteoporosis.
This study determines the effectiveness of C.
caudatus as bone protective agent in postmenopausal osteoporosis rat model.
Thirty-two female rats, aged 3 months old, were divided into 4 groups.
Group one was sham operated (sham) while group two was ovariectomized.
These two groups were given ionized water by forced feeding.
Groups three and four were ovariectomized and given calcium 1% ad libitum and force-fed with C.
caudatus at the dose of 500 mg/kg, respectively.
Treatments were given six days per week for a period of eight weeks.
Body weight was monitored every week and structural bone histomorphometry analyses of the femur bones were performed.
Ovariectomy decreased trabecular bone volume (BV/TV), decreased trabecular number (Tb.N), and increased trabecular separation (Tb.Sp).
Both calcium 1% and 500 mg/kg C.
caudatus reversed the above structural bone histomorphometric parameters to normal level.
C.
caudatus shows better effect compared to calcium 1% on trabecular number (Tb.N) and trabecular separation (Tb.Sp).
Therefore, Cosmos caudatus 500 mg/kg has the potential to act as the therapeutic agent to restore bone damage in postmenopausal women.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mohamed, Norazlina& Gwee Sian Khee, Sharon& Shuid, Ahmad Nazrun& Muhammad, Norliza& Haji Suhaimi, Farihah& Othman, Faizah…[et al.]. 2012. The Effects of Cosmos caudatus on Structural Bone Histomorphometry in Ovariectomized Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1028557
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mohamed, Norazlina…[et al.]. The Effects of Cosmos caudatus on Structural Bone Histomorphometry in Ovariectomized Rats. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-1028557
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mohamed, Norazlina& Gwee Sian Khee, Sharon& Shuid, Ahmad Nazrun& Muhammad, Norliza& Haji Suhaimi, Farihah& Othman, Faizah…[et al.]. The Effects of Cosmos caudatus on Structural Bone Histomorphometry in Ovariectomized Rats. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1028557
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1028557
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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