Value of C-Reactive Protein as a Risk Factor for Acute CoronarySyndrome: A Comparison with Apolipoprotein Concentrations and Lipid Profile
المؤلفون المشاركون
Kozinski, Marek
Fabiszak, Tomasz
Kubica, Jacek
Sawicki, Marcin
Obonska, Karolina
Sypniewska, Grazyna
Stefanska, Anna
Krintus, Magdalena
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-10-16
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Objective.
To investigate whether assessment of C-reactive protein (CRP) and apolipoproteins, besides the traditional lipid profile, enhances the assessment process for the risk of acute coronary syndrome (ACS).
Methods.
The study group consisted of 220 consecutive patients admitted to hospital within the first 6 hours from the onset of chest pain.
Patients were diagnosed with unstable angina (n=96), non-ST-elevation myocardial infarction (NSTEMI; n=57), or ST-elevation myocardial infarction (STEMI; n=67).
ACS patients were compared with 116 healthy volunteers in a case-control study.
The serum was assayed on admission for CRP, apolipoproteins ApoAI and ApoB100, and lipid parameters.
Results.
The highest concentrations of CRP were found in NSTEMI and STEMI, with a median value four-fold higher in ACS patients than in controls (P<0.0001).
Only CRP significantly increased the probability of ACS development (adjusted odds ratio for a 1 mg/L increase 1.90; 95% confidence interval [CI] 1.34–2.89) and explained 90% of the variation for ACS development.
Similarly, we demonstrated the highest diagnostic accuracy for CRP among all investigated markers (area under the curve 0.80; 95% CI 0.75–0.85).
Conclusions.
Our study indicates that CRP superiorly to apolipoproteins and lipid profile facilitates the risk stratification for ACS occurrence.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Krintus, Magdalena& Kozinski, Marek& Stefanska, Anna& Sawicki, Marcin& Obonska, Karolina& Fabiszak, Tomasz…[et al.]. 2012. Value of C-Reactive Protein as a Risk Factor for Acute CoronarySyndrome: A Comparison with Apolipoprotein Concentrations and Lipid Profile. Mediators of Inflammation،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-1029400
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Krintus, Magdalena…[et al.]. Value of C-Reactive Protein as a Risk Factor for Acute CoronarySyndrome: A Comparison with Apolipoprotein Concentrations and Lipid Profile. Mediators of Inflammation No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-1029400
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Krintus, Magdalena& Kozinski, Marek& Stefanska, Anna& Sawicki, Marcin& Obonska, Karolina& Fabiszak, Tomasz…[et al.]. Value of C-Reactive Protein as a Risk Factor for Acute CoronarySyndrome: A Comparison with Apolipoprotein Concentrations and Lipid Profile. Mediators of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-1029400
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1029400
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر