Serum IL-33 Levels Are Associated with Liver Damage in Patients with Chronic Hepatitis C
المؤلفون المشاركون
Jiang, Yanfang
Wang, Juan
Niu, Jun-Qi
Guo, Hui
Sun, Xiguang
Jiang, Zhenyu
Xu, Lijun
Feng, Junyan
Zhao, Pingwei
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-11-02
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Interleukin-33 (IL-33) is associated with the development of Th2 responses.
This study examined the potential role of IL-33 in the pathogenic process of chronic hepatitis C (CHC) in Chinese patients.
The levels of serum IL-33 and sST2 in 154 patients with CHC, 24 with spontaneously resolved HCV (SR-HCV) infection and 20 healthy controls (HC), were analyzed by ELISA.
The concentrations of serum IL-2, IFN-γ, TNF-α, IL-4, IL-6, and IL-10, HCV loads, ALT, AST, and HCV-Ab were measured.
We found that the levels of serum IL-33 in CHC patients were significantly higher than those of SR-HCV and HC but decreased after treatment with interferon for 12 weeks.
More importantly, the levels of serum IL-33 were correlated with the concentrations of ALT and AST in CHC patients.
The levels of serum sST2, as a decoy receptor of IL-33, were significantly higher in CHC and SR-CHC patients than those in HC, and there was no correlation between the levels of serum sST2 and IL-33.
The concentrations of serum IFN-γ and IL-6 in CHC patients were significantly lower than those of SR-HCV.
These data suggest that IL-33 may be a pathogenic factor contributing to CHC-related liver injury.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Juan& Zhao, Pingwei& Guo, Hui& Sun, Xiguang& Jiang, Zhenyu& Xu, Lijun…[et al.]. 2011. Serum IL-33 Levels Are Associated with Liver Damage in Patients with Chronic Hepatitis C. Mediators of Inflammation،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1029447
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Juan…[et al.]. Serum IL-33 Levels Are Associated with Liver Damage in Patients with Chronic Hepatitis C. Mediators of Inflammation No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-1029447
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Juan& Zhao, Pingwei& Guo, Hui& Sun, Xiguang& Jiang, Zhenyu& Xu, Lijun…[et al.]. Serum IL-33 Levels Are Associated with Liver Damage in Patients with Chronic Hepatitis C. Mediators of Inflammation. 2011. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1029447
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1029447
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر