The Potential for Cellular Therapy Combined with Growth Factors in Spinal Cord Injury
المؤلفون المشاركون
Liu, John C.
Avalos, Pablo
Acosta, Frank
Drazin, Doniel G.
Rosner, Jack
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-10-03
دولة النشر
مصر
عدد الصفحات
11
الملخص EN
Any traumatic spinal cord injury (SCI) may cause symptoms ranging from pain to complete loss of motor and sensory functions below the level of the injury.
Currently, there are over 2 million SCI patients worldwide.
The cost of their necessary continuing care creates a burden for the patient, their families, and society.
Presently, few SCI treatments are available and none have facilitated neural regeneration and/or significant functional improvement.
Research is being conducted in the following areas: pathophysiology, cellular therapies (Schwann cells, embryonic stem cells, induced pluripotent stem cells, mesenchymal stem cells, olfactory ensheathing cells), growth factors (BDNF), inhibitory molecules (NG2, myelin protein), and combination therapies (cell grafts and neurotrophins, cotransplantation).
Results are often limited because of the inhibitory environment created following the injury and the limited regenerative potential of the central nervous system.
Therapies that show promise in small animal models may not transfer to nonhuman primates and humans.
None of the research has resulted in remarkable improvement, but many areas show promise.
Studies have suggested that a combination of therapies may enhance results and may be more effective than a single therapy.
This paper reviews and discusses the most promising new SCI research including combination therapies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rosner, Jack& Avalos, Pablo& Acosta, Frank& Liu, John C.& Drazin, Doniel G.. 2012. The Potential for Cellular Therapy Combined with Growth Factors in Spinal Cord Injury. Stem Cells International،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-1030045
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rosner, Jack…[et al.]. The Potential for Cellular Therapy Combined with Growth Factors in Spinal Cord Injury. Stem Cells International No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-1030045
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rosner, Jack& Avalos, Pablo& Acosta, Frank& Liu, John C.& Drazin, Doniel G.. The Potential for Cellular Therapy Combined with Growth Factors in Spinal Cord Injury. Stem Cells International. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-1030045
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1030045
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر