Intensity-Dependent Effect of Treadmill Running on Knee Articular Cartilage in a Rat Model
المؤلفون المشاركون
Liu, Sheng-Yao
Lei, Lei
Li, Zhe
Zhou, Yue-Zhu
Zhan, Li-Qiong
Ni, Guo-Xin
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-22
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
To understand the changes of femoral cartilage in response to treadmill running with different intensities in the hope of differentiating “moderate” and “strenuous” running in a rat model.
Method.
A total of 24 male Wistar rats were randomly assigned into groups of sedentary (SED), low-intensity running (LIR), medium-intensity running (MIR), and high-intensity running (HIR).
Rats in LIR, MIR, and HIR groups underwent 8 weeks’ treadmill running programs.
After sacrificed, femoral condyles were collected to take histomorphometric analysis and immunohistochemistry for collagen II.
Results.
Gross and histological observation showed osteoarthritic changes in group HIR.
In comparison to SED group, there was significant increase in cartilage thickness, number of chondrocytes, and GAG content in groups LIR and MIR.
Conversely, decrease in cartilage thickness, chondrocyte number, and GAG content was found in rats of HIR group, without significant difference though.
In addition, in comparison to SED group, HIR group exhibited disorganization of collagen fibril and significantly lower content of collagen type II.
Conclusion.
An intensity-dependent effect was suggested on the articular cartilage.
Our results also demonstrated that running with low-to-medium intensity applied in the present study should be regarded as “moderate” running, whereas high-intensity running as “strenuous” running.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ni, Guo-Xin& Liu, Sheng-Yao& Lei, Lei& Li, Zhe& Zhou, Yue-Zhu& Zhan, Li-Qiong. 2013. Intensity-Dependent Effect of Treadmill Running on Knee Articular Cartilage in a Rat Model. BioMed Research International،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1030153
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ni, Guo-Xin…[et al.]. Intensity-Dependent Effect of Treadmill Running on Knee Articular Cartilage in a Rat Model. BioMed Research International No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1030153
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ni, Guo-Xin& Liu, Sheng-Yao& Lei, Lei& Li, Zhe& Zhou, Yue-Zhu& Zhan, Li-Qiong. Intensity-Dependent Effect of Treadmill Running on Knee Articular Cartilage in a Rat Model. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1030153
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1030153
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر