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Genetic and Functional Profiling of Crohn's Disease: Autophagy Mechanism and Susceptibility to Infectious Diseases
المؤلفون المشاركون
Marcuzzi, Annalisa
Crovella, Sérgio
Tommasini, A.
Bianco, Anna Monica
Girardelli, Martina
Martelossi, Stefano
Monasta, Lorenzo
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-05-08
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Crohn's disease is a complex disease in which genome, microbiome, and environment interact to produce the immunological background of the disease.
Disease in childhood is more extensive and characterized by a rapid progression, leading to severe repercussions in the course of the disorder.
Several genetic variations have been associated with an increased risk of developing the disease and most of these are also implicated in other autoimmune disorders.
The gut has many tiers of defense against incursion by luminal microbes, including the epithelial barrier and the innate and adaptive immune responses.
Moreover, recent evidence shows that bacterial and viral infections, as well as inflammasome genes and genes involved in the autophagy process, are implicated in Crohn's disease pathogenesis.
The aim of this review is to establish how much the diagnostic system can improve, thus increasing the success of Crohn's disease diagnosis.
The major expectation for the near future is to be able to anticipate the possible consequences of the disease already in childhood, thus preventing associated complications, and to choose the best treatment for each patient.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Marcuzzi, Annalisa& Bianco, Anna Monica& Girardelli, Martina& Tommasini, A.& Martelossi, Stefano& Monasta, Lorenzo…[et al.]. 2013. Genetic and Functional Profiling of Crohn's Disease: Autophagy Mechanism and Susceptibility to Infectious Diseases. BioMed Research International،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1030338
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Marcuzzi, Annalisa…[et al.]. Genetic and Functional Profiling of Crohn's Disease: Autophagy Mechanism and Susceptibility to Infectious Diseases. BioMed Research International No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-1030338
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Marcuzzi, Annalisa& Bianco, Anna Monica& Girardelli, Martina& Tommasini, A.& Martelossi, Stefano& Monasta, Lorenzo…[et al.]. Genetic and Functional Profiling of Crohn's Disease: Autophagy Mechanism and Susceptibility to Infectious Diseases. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1030338
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1030338
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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