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Preserved Transcallosal Inhibition to Transcranial Magnetic Stimulation in Nondemented Elderly Patients with Leukoaraiosis
المؤلفون المشاركون
Lanza, Giuseppe
Bella, Rita
Giuffrida, Salvatore
Cantone, Mariagiovanna
Pennisi, Giovanni
Spampinato, Concetto
Giordano, Daniela
Raggi, Alberto
Pennisi, Manuela
Malaguarnera, Giulia
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-25
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Structural corpus callosum (CC) changes in patients with leukoaraiosis (LA) are significantly associated with cognitive and motor impairment.
The aim of this study is to investigate the transcallosal fibers functioning by means of transcranial magnetic stimulation (TMS) in elderly patients with LA.
The resting motor threshold (rMT), the motor-evoked potentials (MEPs), and the controlateral (cSP) and ipsilateral silent periods (iSP) were determined using single-pulse TMS in 15 patients and 15 age-matched controls.
The neuropsychological profile and the vascular burden at brain magnetic resonance imaging (MRI) were concomitantly explored.
Patients reported abnormal scores at tests evaluating executive control functions.
No significant difference was found in TMS measures of intra- and intercortical excitability.
No CC lesion was evident at MRI.
Transcallosal inhibitory mechanisms to TMS seem to be spared in LA patients, a finding which is in line with neuroimaging features and suggests a functional integrity of the CC despite the ischemic interruption of corticosubcortical loops implicated in cognition and behavior.
The observed neurophysiological finding differs from that reported in degenerative dementia, even in the preclinical or early stage.
In our group of patients, the pure extent of LA is more related to impairment of frontal lobe abilities rather than functional callosal changes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lanza, Giuseppe& Bella, Rita& Giuffrida, Salvatore& Cantone, Mariagiovanna& Pennisi, Giovanni& Spampinato, Concetto…[et al.]. 2013. Preserved Transcallosal Inhibition to Transcranial Magnetic Stimulation in Nondemented Elderly Patients with Leukoaraiosis. BioMed Research International،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1030427
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lanza, Giuseppe…[et al.]. Preserved Transcallosal Inhibition to Transcranial Magnetic Stimulation in Nondemented Elderly Patients with Leukoaraiosis. BioMed Research International No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-1030427
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lanza, Giuseppe& Bella, Rita& Giuffrida, Salvatore& Cantone, Mariagiovanna& Pennisi, Giovanni& Spampinato, Concetto…[et al.]. Preserved Transcallosal Inhibition to Transcranial Magnetic Stimulation in Nondemented Elderly Patients with Leukoaraiosis. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1030427
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1030427
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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