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Genotypically Different Clones of Staphylococcus aureus Are Diverse in the Antimicrobial Susceptibility Patterns and Biofilm Formations
المؤلفون المشاركون
Nathan, Jayakayatri Jeevajothi
Karunanidhi, Arunkumar
Shamsudin, Mariana Nor
Sekawi, Zamberi
Mateg Ali, Alreshidi
Thian Lung, Leslie Than
Pei Pei, Chong
Ghaznavi-Rad, Ehsanollah
Hamat, Rukman Awang
Atshan, Salman Sahab
Nor Shamsudin, Mariana
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-25
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
This study evaluated whether genotypically different clinical isolates of S.
aureus have similar susceptibilities to individual antibiotics.
It further aims to check the impact of biofilm on the in vitro activity of vancomycin, daptomycin, linezolid, and tigecycline against S.
aureus clones.
The study used a total of 60 different clinical MSSA and MRSA isolates.
Susceptibilities were performed in planktonic cultures by macrobroth dilution and epsilon-test (E test) system.
Biofilm production was determined using an adherent plate assay.
The efficacy of antimicrobial activities against biofilms formation was checked using confocal laser scanning microscopy (CLSM).
The study found that similar and different spa, MLST, and SCCmec types displayed high variation in their susceptibilities to antibiotics with tigecycline and daptomycin being the most effective.
The biofilms were found resistant to high concentrations of most antibiotics tested with daptomycin being the most effective drug used in adhesive biofilms.
A considerable difference exists among similar and various clone types against antibiotics tested.
This variation could have contributed to the degree of virulence even within the same clonal genotype and enhanced heterogeneity in the infection potential.
Thus, the development of a rapid and precise identification profile for each clone in human infections is important.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Atshan, Salman Sahab& Shamsudin, Mariana Nor& Thian Lung, Leslie Than& Sekawi, Zamberi& Pei Pei, Chong& Karunanidhi, Arunkumar…[et al.]. 2013. Genotypically Different Clones of Staphylococcus aureus Are Diverse in the Antimicrobial Susceptibility Patterns and Biofilm Formations. BioMed Research International،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1030614
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Atshan, Salman Sahab…[et al.]. Genotypically Different Clones of Staphylococcus aureus Are Diverse in the Antimicrobial Susceptibility Patterns and Biofilm Formations. BioMed Research International No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-1030614
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Atshan, Salman Sahab& Shamsudin, Mariana Nor& Thian Lung, Leslie Than& Sekawi, Zamberi& Pei Pei, Chong& Karunanidhi, Arunkumar…[et al.]. Genotypically Different Clones of Staphylococcus aureus Are Diverse in the Antimicrobial Susceptibility Patterns and Biofilm Formations. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1030614
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1030614
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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