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Development of a Modelling to Correlate Site and Diameter of Brain Metastases with Hippocampal Sparing Using Volumetric Modulated Arc Therapy
المؤلفون المشاركون
Balducci, Mario
Chiesa, Silvia
Azario, Luigi
Gaudino, Simona
Cellini, Francesco
Colosimo, Cesare
Valentini, Vincenzo
Mattiucci, Gian Carlo
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-10-09
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Purpose.
To correlate site and diameter of brain metastases with hippocampal sparing in patients treated by RapidArc (RA) technique on whole brain with simultaneously integrated boost (SIB).
Methods and Materials.
An RA plan was calculated for brain metastases of 1-2-3 cm of diameter.
The whole brain dose was 32.25 Gy (15 fractions), and SIB doses to brain metastases were 63 Gy (2 and 3 cm) or 70.8 Gy (1 cm).
Plans were optimized and evaluated for conformity, target coverage, prescription isodose to target volume, homogeneity index, and hippocampal sparing.
Results.
Fifteen brain lesions and RA plan were generated.
Hippocampal volume was 4.09 cm3, and hippocampal avoidance volume was 17.50 cm3.
Related to site of metastases, the mean hippocampal dose was 9.68 Gy2 for occipital lobe, 10.56 Gy2 for frontal lobe, 10.56 Gy2 for parietal lobe, 10.94 Gy2 for deep brain structures, and 40.44 Gy2 for temporal lobe.
The mean hippocampal dose was 9.45 Gy2, 10.15 Gy2, and 11.70 Gy2 for diameter’s metastases of 1.2 and 3 cm, respectively, excluding results relative to temporal brain lesions.
Conclusions.
Location more than size of metastases can adversely influence the hippocampus sparing.
Further investigation is necessary to meet definitive considerations.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chiesa, Silvia& Balducci, Mario& Azario, Luigi& Gaudino, Simona& Cellini, Francesco& Mattiucci, Gian Carlo…[et al.]. 2013. Development of a Modelling to Correlate Site and Diameter of Brain Metastases with Hippocampal Sparing Using Volumetric Modulated Arc Therapy. BioMed Research International،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1030668
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chiesa, Silvia…[et al.]. Development of a Modelling to Correlate Site and Diameter of Brain Metastases with Hippocampal Sparing Using Volumetric Modulated Arc Therapy. BioMed Research International No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1030668
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chiesa, Silvia& Balducci, Mario& Azario, Luigi& Gaudino, Simona& Cellini, Francesco& Mattiucci, Gian Carlo…[et al.]. Development of a Modelling to Correlate Site and Diameter of Brain Metastases with Hippocampal Sparing Using Volumetric Modulated Arc Therapy. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1030668
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1030668
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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