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Microbiological Profile of Adenoid Hypertrophy Correlates to Clinical Diagnosis in Children
المؤلفون المشاركون
Sziklai, István
Szalmás, Anita
Papp, Zoltán
Csomor, Péter
Kónya, József
Szekanecz, Zoltán
Karosi, Tamás
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-23
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Objective.
Adenoid hypertrophy is a common condition in childhood, which may be associated with recurring acute otitis media (RAOM), otitis media with effusion (OME), and obstructive sleep apnea syndrome (OSAS).
These different clinical characteristics have some clinical overlap; however, they might be explained by distinct immunologic and infectious profiles and result in various histopathologic findings of adenoid specimens.
Methods.
A total of 59 children with adenoid hypertrophy undergoing adenoidectomy were studied.
Three series of identical adenoid specimens were processed to hematoxylin-eosin (H.E.) and Gram staining and to respiratory virus specific real-time PCR, respectively.
Results.
According to the clinical characteristics, patients were recruited into three groups: RAOM (n=25), OME (n=19), and OSAS (n=15).
Bacterial biofilms were detected in 21 cases, while at least one of the studied respiratory viruses was detected in 52 specimens.
RAOM cases were significantly associated with biofilm existence (n=20, P<0.001).
In contrast, OME group was characterized by the absence of bacterial biofilm and by normal mucosa.
Showing a statistically significant correlation, all OME cases were positive for human bocavirus (HBoV, P<0.001).
Conclusions.
Bacterial biofilms might contribute to the damage of respiratory epithelium and recurring acute infections resulting in RAOM.
In OME cases persisting respiratory viruses, mainly HBoV, can cause subsequent lymphoid hyperplasia leading to ventilation disorders and impaired immunoreactivity of the middle ear cleft.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Szalmás, Anita& Papp, Zoltán& Csomor, Péter& Kónya, József& Sziklai, István& Szekanecz, Zoltán…[et al.]. 2013. Microbiological Profile of Adenoid Hypertrophy Correlates to Clinical Diagnosis in Children. BioMed Research International،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1030739
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Szalmás, Anita…[et al.]. Microbiological Profile of Adenoid Hypertrophy Correlates to Clinical Diagnosis in Children. BioMed Research International No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-1030739
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Szalmás, Anita& Papp, Zoltán& Csomor, Péter& Kónya, József& Sziklai, István& Szekanecz, Zoltán…[et al.]. Microbiological Profile of Adenoid Hypertrophy Correlates to Clinical Diagnosis in Children. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1030739
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1030739
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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