Role of Digoxin-Like Immunoreactive Substance in the Pathogenesis of Transient Tachypnea of Newborn
المؤلفون المشاركون
Yalaz, Mehmet
Kultursay, Nilgun
Levent, Erturk
Calkavur, Sebnem
Akisu, Mete
Olukman, Murat
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-07
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
Transient tachypnea of newborn (TTN) is usually observed in term or near-term infants.
It constitutes an important part of the respiratory distress cases observed in the neonatal intensive care unit (NICU).
Aim.
This paper examines the effects of digoxin-like immunoreactive substance (DLIS) on fluid and ion balance, hemodynamic and echocardiographic parameters of neonates with TTN.
Methods.
Plasma DLIS, Na+, K+, urea, creatinine, serum and urine osmolarity, urine FeNa+, 24-hour urine output, echocardiographic investigation and mean blood pressure, and clinical parameters of disease severity were recorded in TTN group and compared with control on the 1st and 7th days of their lives.
Results.
Plasma DLIS levels were statistically higher in TTN group (0.66±0.37 ng/mL) compared to control group (0.24±0.20 ng/mL) both on the 1st day (P<0.01) and the 7th day (P<0.05).
For TTN group, significant correlation was found between plasma DLIS levels and maximum respiratory rate, duration of tachypnea, and length of hospitalization on the 1st day.
Plasma DLIS levels were correlated negatively with serum osmolarity levels.
Plasma DLIS levels were positively correlated with urine output, urinary FeNa+ levels, cardiac output, left ventricles end diastolic diameters, and right ventricles end diastolic diameters.
Conclusions.
Increased DLIS levels were correlated with disease severity in cases with TTN.
This increase may be a primary or secondary event in the disease progress.
It may help reduce the fluid overload due to already disturbed cardiac functions in patients by increasing urine output and natriuresis; however it may also contribute to disease pathogenesis, by inhibiting alveolar Na+-K+-ATPase which further decreases fetal alveolar fluid resorption.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yalaz, Mehmet& Levent, Erturk& Olukman, Murat& Calkavur, Sebnem& Akisu, Mete& Kultursay, Nilgun. 2013. Role of Digoxin-Like Immunoreactive Substance in the Pathogenesis of Transient Tachypnea of Newborn. BioMed Research International،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1030816
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yalaz, Mehmet…[et al.]. Role of Digoxin-Like Immunoreactive Substance in the Pathogenesis of Transient Tachypnea of Newborn. BioMed Research International No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-1030816
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yalaz, Mehmet& Levent, Erturk& Olukman, Murat& Calkavur, Sebnem& Akisu, Mete& Kultursay, Nilgun. Role of Digoxin-Like Immunoreactive Substance in the Pathogenesis of Transient Tachypnea of Newborn. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1030816
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1030816
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر