Proliferative Activity in Libyan Breast Cancer with Comparison to European and Central African Patients
المؤلفون المشاركون
Boder, Jamela
Abdalla, Fathi
Buhmeida, Abdelbaset
Collan, Yrjö
Elfagieh, M.
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-11
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
We evaluated the relation of proliferative indices with clinicopathological features and prognosis in breast cancer (BC) of Libyan female patients.
The data were compared with corresponding results in Finland and Nigeria.
Patients and Methods.
Histological samples of breast cancer from 130 patients were retrospectively studied.
Mitotic activity index (MAI) and standardized mitotic index (SMI) were estimated.
Results.
There were statistically significant correlations between the proliferative indices and most clinicopathological features, with the strongest association observed for histological grade (P=0.01 for SMI and P=0.003 for MAI).
The proliferative differences between Libyan, Nigerian, and Finnish population were prominent.
The mean values of SMI and MAI in Libyan BC patients were 32.1 mitotic figures per square millimeter and 27.3 mitotic figures per 10 high-power fields, respectively.
This is clearly lower than those in Nigeria but much higher than those in Finland.
The differences between countries are seen in whole material and are also present in subgroups.
The results indicated that mitotic activities can be reliable prognostic indicators in Libyan BCs, as they were among Finnish and Nigerian females.
Univariate and multivariate analyses found at cut-offs of 19 and 44 mitosis/mm2 of SMI were the most significant prognostic factors.
Conclusions.
Proliferative indices with careful estimation of the MAI and SMI could be applied as quantitative criteria for Libyan BC to separate the patients into good, moderate, and bad prognosis groups.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Boder, Jamela& Abdalla, Fathi& Elfagieh, M.& Buhmeida, Abdelbaset& Collan, Yrjö. 2013. Proliferative Activity in Libyan Breast Cancer with Comparison to European and Central African Patients. BioMed Research International،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1030968
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Boder, Jamela…[et al.]. Proliferative Activity in Libyan Breast Cancer with Comparison to European and Central African Patients. BioMed Research International No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-1030968
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Boder, Jamela& Abdalla, Fathi& Elfagieh, M.& Buhmeida, Abdelbaset& Collan, Yrjö. Proliferative Activity in Libyan Breast Cancer with Comparison to European and Central African Patients. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1030968
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1030968
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر