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The Assessment of Proteus mirabilis Susceptibility to Ceftazidime and Ciprofloxacin and the Impact of These Antibiotics at Subinhibitory Concentrations on Proteus mirabilis Biofilms
المؤلفون المشاركون
Kwiecińska-Piróg, Joanna
Zniszczol, Katarzyna
Gospodarek, Eugenia
Skowron, Krzysztof
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-12
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Rods of the Proteus genus are commonly isolated from patients, especially from the urinary tracts of the catheterised patients.
The infections associated with biomaterials are crucial therapeutic obstacles, due to the bactericidal resistance of the biofilm.
The aim of this study was to assess the susceptibility of P.
mirabilis planktonic forms to ciprofloxacin and ceftazidime, the ability to form biofilm, and the impact of chosen sub-MIC concentrations of these antibiotics on biofilm at different stages of its formation.
The research included 50 P.
mirabilis strains isolated from wounds and the urinary tracts from patients of the University Hospital No.
1 in Bydgoszcz.
The assessment of susceptibility to ciprofloxacin and ceftazidime was conducted using micromethods.
The impact of sub-MIC concentrations of the chosen antibiotics on the biofilm was measured using the TTC method.
The resistance to ciprofloxacin was confirmed for 20 strains (40.0%) while to ceftazidime for 32 (64.0%) of the tested P.
mirabilis strains.
All of the tested strains formed biofilm: 24.0% weakly, 26.0% moderately, and 50.0% strongly.
It was determined that ciprofloxacin and ceftazidime caused eradication of the biofilm.
Moreover, the connection between origin of the strains, biofilm maturity level, and resistance to antibiotics was proved.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kwiecińska-Piróg, Joanna& Skowron, Krzysztof& Zniszczol, Katarzyna& Gospodarek, Eugenia. 2013. The Assessment of Proteus mirabilis Susceptibility to Ceftazidime and Ciprofloxacin and the Impact of These Antibiotics at Subinhibitory Concentrations on Proteus mirabilis Biofilms. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1031113
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kwiecińska-Piróg, Joanna…[et al.]. The Assessment of Proteus mirabilis Susceptibility to Ceftazidime and Ciprofloxacin and the Impact of These Antibiotics at Subinhibitory Concentrations on Proteus mirabilis Biofilms. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1031113
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kwiecińska-Piróg, Joanna& Skowron, Krzysztof& Zniszczol, Katarzyna& Gospodarek, Eugenia. The Assessment of Proteus mirabilis Susceptibility to Ceftazidime and Ciprofloxacin and the Impact of These Antibiotics at Subinhibitory Concentrations on Proteus mirabilis Biofilms. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1031113
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1031113
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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