The Predictive Value of Adrenomedullin for Development of Severe Sepsis and Septic Shock in Emergency Department
المؤلفون المشاركون
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-08-04
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
The aim of the study was to assess adrenomedullin (AM) as a predictor for development of severe sepsis and septic shock in emergency department (ED).
Method.
From December 2011 to October 2012, 372 consecutive septic patients admitted to ED were enrolled.
AM was examined in every patient.
All patients were followed up for 3 days.
The outcome variable was development of severe sepsis or septic shock.
The predictive ability of AM was evaluated by binary logistic regression analysis and receiver operating characteristic (ROC) curve.
Result.
On admission, the differences of AM among patients with different comorbidities, infections, and culture results were not significant.
AM level was higher in patients who progressed than in who did not (41.63 ± 6.55 versus 31.31 ± 7.71 ng/L, P<0.001).
AM was the only independent predictor of outcome.
The area under ROC curve of AM was 0.847.
With a cutoff value of 41.24 ng/L, the sensitivity was 67.6%, the specificity was 90.0%, the positive predictive value was 61.5%, the negative predictive value was 92.2%, the positive likelihood ratio was 6.78, and the negative likelihood ratio was 0.36.
Conclusion.
Adrenomedullin is valuable for predicting development of severe sepsis and septic shock in ED.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Yun-Xia& Li, Chun-Sheng. 2013. The Predictive Value of Adrenomedullin for Development of Severe Sepsis and Septic Shock in Emergency Department. BioMed Research International،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1031146
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Yun-Xia& Li, Chun-Sheng. The Predictive Value of Adrenomedullin for Development of Severe Sepsis and Septic Shock in Emergency Department. BioMed Research International No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1031146
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Yun-Xia& Li, Chun-Sheng. The Predictive Value of Adrenomedullin for Development of Severe Sepsis and Septic Shock in Emergency Department. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1031146
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1031146
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر