Serum Paraoxonase 1 Activity Is Associated with Fatty Acid Composition of High Density Lipoprotein
المؤلفون المشاركون
Emami Razavi, Amirnader
Pourfarzam, Morteza
Ani, Mohsen
Naderi, Gholam Ali
Basati, Gholam
Dinani, Narges Jafari
Abdi, Soheila
Mansourian, Marjan
Boshtam, Maryam
Asgary, Sedigheh
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-12
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Introduction.
Cardioprotective effect of high density lipoprotein (HDL) is, in part, dependent on its related enzyme, paraoxonase 1 (PON1).
Fatty acid composition of HDL could affect its size and structure.
On the other hand, PON1 activity is directly related to the structure of HDL.
This study was designed to investigate the association between serum PON1 activity and fatty acid composition of HDL in healthy men.
Methods.
One hundred and forty healthy men participated in this research.
HDL was separated by sequential ultracentrifugation, and its fatty acid composition was analyzed by gas chromatography.
PON1 activity was measured spectrophotometrically using paraxon as substrate.
Results.
Serum PON1 activity was directly correlated with the amount of stearic acid and dihomo-gamma-linolenic acid (DGLA).
PON1/HDL-C was directly correlated with the amount of miristic acid, stearic acid, and DGLA and was inversely correlated with total amount of ω6 fatty acids of HDL.
Conclusion.
The fatty acid composition of HDL could affect the activity of its associated enzyme, PON1.
As dietary fats are the major determinants of serum lipids and lipoprotein composition, consuming some special dietary fatty acids may improve the activity of PON1 and thereby have beneficial effects on health.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Boshtam, Maryam& Emami Razavi, Amirnader& Pourfarzam, Morteza& Ani, Mohsen& Naderi, Gholam Ali& Basati, Gholam…[et al.]. 2013. Serum Paraoxonase 1 Activity Is Associated with Fatty Acid Composition of High Density Lipoprotein. Disease Markers،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1031211
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Boshtam, Maryam…[et al.]. Serum Paraoxonase 1 Activity Is Associated with Fatty Acid Composition of High Density Lipoprotein. Disease Markers No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1031211
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Boshtam, Maryam& Emami Razavi, Amirnader& Pourfarzam, Morteza& Ani, Mohsen& Naderi, Gholam Ali& Basati, Gholam…[et al.]. Serum Paraoxonase 1 Activity Is Associated with Fatty Acid Composition of High Density Lipoprotein. Disease Markers. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1031211
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1031211
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر