Predictive Value of Admission N-Terminal Pro-B-Type Natriuretic Peptide and Renal Function in Older People Hospitalized for Dyspnoea
المؤلفون المشاركون
Zuliani, Giovanni
De Giorgi, Alfredo
Volpato, Stefano
Portaluppi, Francesco
Manfredini, Roberto
Fabbian, Fabio
Pala, Marco
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-14
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
We investigated the relationship between NT-pro-BNP, glomerular filtration rate (GFR), and all-cause mortality rates in a cohort of older people discharged from an internal medicine unit after admission for dyspnoea.
Patients and Methods.
NT-pro-BNP was evaluated in serum samples of 134 patients aged 80 ± 6 years who presented to a single academic centre with worsening dyspnoea.
History data and anthropometric, clinical, and biochemical parameters including GFR were collected at the time of admission.
119 out of 134 were discharged alive from hospital and were included in the follow-up of 779 ± 370 days.
Results.
35 out of 119 subjects died after a follow-up of 266 ± 251 days.
Cox proportional hazards model showed that GFR and Ln (NT-pro-BNP) were predictors for all-cause mortality with estimated hazard ratios of 0.969 (95% confidence interval: 0.950–0.988; P=0.001) and 2.360 (95% confidence interval: 1.208–4.610; P=0.012), respectively.
Patients characterized by high NT-pro-BNP levels and GFR ≥ 60 mL/min/1.73 m2 showed a dramatic reduction in survival duration compared with the groups with different combinations of the two variables (P=0.008).
Conclusions.
In the elderly, NT-pro-BNP and GFR are predictors of all-cause mortality after admission because of dyspnoea.
Since the fact that subjects with high NT-pro-BNP and GFR ≥ 60 mL/min/1.73 m2 exhibited a reduced survival, high admission NT-pro-BNP suggests future negative outcome.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fabbian, Fabio& De Giorgi, Alfredo& Pala, Marco& Volpato, Stefano& Portaluppi, Francesco& Zuliani, Giovanni…[et al.]. 2013. Predictive Value of Admission N-Terminal Pro-B-Type Natriuretic Peptide and Renal Function in Older People Hospitalized for Dyspnoea. Disease Markers،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1031217
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fabbian, Fabio…[et al.]. Predictive Value of Admission N-Terminal Pro-B-Type Natriuretic Peptide and Renal Function in Older People Hospitalized for Dyspnoea. Disease Markers No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1031217
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fabbian, Fabio& De Giorgi, Alfredo& Pala, Marco& Volpato, Stefano& Portaluppi, Francesco& Zuliani, Giovanni…[et al.]. Predictive Value of Admission N-Terminal Pro-B-Type Natriuretic Peptide and Renal Function in Older People Hospitalized for Dyspnoea. Disease Markers. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1031217
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1031217
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر