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Fecal S100A12 in Healthy Infants and Children
المؤلفون المشاركون
Ehn, M.
Leach, Steven T.
Lemberg, Daniel A.
Day, Andrew Stewart
Gearry, R. B.
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-15
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background and Aims.
Fecal S100A12 is shown to be a useful noninvasive marker of gut inflammation.
However, the studies to date have not characterised the patterns of expression in healthy young children.
This study aimed to determine S100A12 levels in infants and children without symptoms of underlying gut disease.
Methods.
Stool samples were collected from healthy infants (<12 months) and children without gastrointestinal symptoms.
Faecal S100A12 was measured by immunoassay.
Results.
Fifty-six children were recruited.
Serial samples were obtained from seven term infants over the first 6 months of life.
Single samples were obtained from 49 healthy children ranging from 0.16 to 13.8 years of age.
Median S100A12 levels were 0.5 mg/kg (ranging from 0.39 to 25) in the healthy children, with high values (>10 mg/kg) in five infants only.
There was no variation between gender.
Median S100A12 levels in healthy infants remained below the established normal cut-off from birth to six months of age.
Conclusion.
S100A12 levels in well infants and children are almost exclusively lower than the standard cut-off.
Transiently higher levels may be seen in early infancy.
An elevated level of S100A12 in children older than 12 months of age is likely to represent organic gut disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Day, Andrew Stewart& Ehn, M.& Gearry, R. B.& Lemberg, Daniel A.& Leach, Steven T.. 2013. Fecal S100A12 in Healthy Infants and Children. Disease Markers،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1031232
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Day, Andrew Stewart…[et al.]. Fecal S100A12 in Healthy Infants and Children. Disease Markers No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-1031232
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Day, Andrew Stewart& Ehn, M.& Gearry, R. B.& Lemberg, Daniel A.& Leach, Steven T.. Fecal S100A12 in Healthy Infants and Children. Disease Markers. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1031232
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1031232
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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