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Is CA72-4 a Useful Biomarker in Differential Diagnosis between Ovarian Endometrioma and Epithelial Ovarian Cancer?
المؤلفون المشاركون
Porpora, Maria Grazia
Manganaro, Lucia
Anastasi, Emanuela
Granato, Teresa
Frati, Luigi
Panici, Pierluigi Benedetti
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-22
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
Surgical excision of ovarian endometriomas in patients desiring pregnancy has recently been criticized because of the risk of damage to healthy ovarian tissue and consequent reduction of ovarian reserve.
A correct diagnosis in cases not scheduled for surgery is therefore mandatory in order to avoid unexpected ovarian cancer misdiagnosis.
Endometriosis is often associated with high levels of CA125.
This marker is therefore not useful for discriminating ovarian endometrioma from ovarian malignancy.
The aim of this study was to establish if the serum marker CA72-4 could be helpful in the differential diagnosis between ovarian endometriosis and epithelial ovarian cancer.
Methods.
Serums CA125 and CA72-4 were measured in 72 patients with ovarian endometriomas and 55 patients with ovarian cancer.
Results.
High CA125 concentrations were observed in patients with ovarian endometriosis and in those with ovarian cancer.
A marked difference in CA72-4 values was observed between women with ovarian cancer (71.0%) and patients with endometriosis (13.8%) (P<0.0001).
Conclusions.
This study suggests that CA72-4 determination can be useful to confirm the benign nature of ovarian endometriomas in women with high CA125 levels.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Anastasi, Emanuela& Manganaro, Lucia& Granato, Teresa& Panici, Pierluigi Benedetti& Frati, Luigi& Porpora, Maria Grazia. 2013. Is CA72-4 a Useful Biomarker in Differential Diagnosis between Ovarian Endometrioma and Epithelial Ovarian Cancer?. Disease Markers،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1031241
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Anastasi, Emanuela…[et al.]. Is CA72-4 a Useful Biomarker in Differential Diagnosis between Ovarian Endometrioma and Epithelial Ovarian Cancer?. Disease Markers No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-1031241
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Anastasi, Emanuela& Manganaro, Lucia& Granato, Teresa& Panici, Pierluigi Benedetti& Frati, Luigi& Porpora, Maria Grazia. Is CA72-4 a Useful Biomarker in Differential Diagnosis between Ovarian Endometrioma and Epithelial Ovarian Cancer?. Disease Markers. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1031241
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1031241
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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