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Fabrication of Novel Biodegradable α-Tricalcium Phosphate Cement Set by Chelating Capability of Inositol Phosphate and Its Biocompatibility
المؤلفون المشاركون
Konishi, Toshiisa
Mizumoto, Minori
Honda, Michiyo
Horiguchi, Yukiko
Oribe, Kazuya
Morisue, Hikaru
Aizawa , Mamoru
Toyama, Yoshiaki
Matsumoto, Morio
Ishii, Ken
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-05-27
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Biodegradable α-tricalcium phosphate (α-TCP) cement based on the chelate-setting mechanism of inositol phosphate (IP6) was developed.
This paper examined the effect of the milling time of α-TCP powder on the material properties of the cement.
In addition, biocompatibility of the result cement in vitro using osteoblasts and in vivo using rabbit models will be studied as well.
The α-TCP powders were ballmilled using ZrO2 beads in pure water for various durations up to 270 minutes, with a single-phase α-TCP obtained at ballmilling for 120 minutes.
The resulting cement was mostly composed of α-TCP phase, and the compressive strength of the cement was 8.5±1.1 MPa, which suggested that the cements set with keeping the crystallite phase of starting cement powder.
The cell-culture test indicated that the resulting cements were biocompatible materials.
In vivo studies showed that the newly formed bones increased with milling time at a slight distance from the cement specimens and grew mature at 24 weeks, and the surface of the cement was resorbed by tartrate-resistant acid phosphatase-(TRAP-)positive osteoclast-like cells until 24 weeks of implantation.
The present α-TCP cement is promising for application as a novel paste-like artificial bone with biodegradability and osteoconductivity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Konishi, Toshiisa& Mizumoto, Minori& Honda, Michiyo& Horiguchi, Yukiko& Oribe, Kazuya& Morisue, Hikaru…[et al.]. 2013. Fabrication of Novel Biodegradable α-Tricalcium Phosphate Cement Set by Chelating Capability of Inositol Phosphate and Its Biocompatibility. Journal of Nanomaterials،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1031600
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Konishi, Toshiisa…[et al.]. Fabrication of Novel Biodegradable α-Tricalcium Phosphate Cement Set by Chelating Capability of Inositol Phosphate and Its Biocompatibility. Journal of Nanomaterials No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-1031600
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Konishi, Toshiisa& Mizumoto, Minori& Honda, Michiyo& Horiguchi, Yukiko& Oribe, Kazuya& Morisue, Hikaru…[et al.]. Fabrication of Novel Biodegradable α-Tricalcium Phosphate Cement Set by Chelating Capability of Inositol Phosphate and Its Biocompatibility. Journal of Nanomaterials. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1031600
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1031600
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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