Profiling the Prognosis of Gastric Cancer Patients: Is It Worth Correlating the Survival with the ClinicalPathological and Molecular Features of Gastric Cancers?
المؤلفون المشاركون
Mercantini, Paolo
Ferri, Mario
La Torre, Marco
Sparagna, Alessandra
Tarantino, Giulia
Romiti, Adriana
Pilozzi, Emanuela
Ziparo, Vincenzo
Balducci, Genoveffa
Lorenzon, Laura
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-24
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Background.
The prognosis of gastric cancer patients still remains poor.
The aim of this study was investigating the prognostic value of several clinical/pathological/molecular features in a consecutive series of gastric cancers.
Methods.
150 R0 gastrectomies plus 77 gastric cancer patients evaluated for the HER2 overexpression were selected.
Survival was calculated and patients stratified according to the stage, the T-stage, the LNRs, the LNH, and the HER2 scoring system.
ROC curves were calculated in order to compare the performance of the LRN and LNH systems.
Results.
Prognosis correlated with the stage and with the T-stage.
We documented a statistical correlation between the LNRs and the survival.
Conversely, a LNH > 15 did not correlate with the outcomes.
The ROC curves documented a significant performance of the LRN system, whereas a statistical correlation was documented for the LNH exclusively with the endpoint of disease-free survival.
We documented a trend of worse prognosis for patients with an HER2 overexpression, even though it was not of statistical value.
Conclusion.
The LNR and the evaluation of the HER2 overexpression might be useful since they correlate with survival, might identify patients with a higher risk of recurrence, and might select patients for a tailored medical treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lorenzon, Laura& Mercantini, Paolo& Ferri, Mario& La Torre, Marco& Sparagna, Alessandra& Balducci, Genoveffa…[et al.]. 2013. Profiling the Prognosis of Gastric Cancer Patients: Is It Worth Correlating the Survival with the ClinicalPathological and Molecular Features of Gastric Cancers?. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1032643
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lorenzon, Laura…[et al.]. Profiling the Prognosis of Gastric Cancer Patients: Is It Worth Correlating the Survival with the ClinicalPathological and Molecular Features of Gastric Cancers?. The Scientific World Journal No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1032643
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lorenzon, Laura& Mercantini, Paolo& Ferri, Mario& La Torre, Marco& Sparagna, Alessandra& Balducci, Genoveffa…[et al.]. Profiling the Prognosis of Gastric Cancer Patients: Is It Worth Correlating the Survival with the ClinicalPathological and Molecular Features of Gastric Cancers?. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1032643
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1032643
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر