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Pathophysiology of Spasticity: Implications for Neurorehabilitation
المؤلفون المشاركون
Trompetto, Carlo
Mori, Laura
Pelosin, Elisa
Currà, Antonio
Molfetta, Luigi
Abbruzzese, Giovanni
Marinelli, Lucio
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-10-30
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Spasticity is the velocity-dependent increase in muscle tone due to the exaggeration of stretch reflex.
It is only one of the several components of the upper motor neuron syndrome (UMNS).
The central lesion causing the UMNS disrupts the balance of supraspinal inhibitory and excitatory inputs directed to the spinal cord, leading to a state of disinhibition of the stretch reflex.
However, the delay between the acute neurological insult (trauma or stroke) and the appearance of spasticity argues against it simply being a release phenomenon and suggests some sort of plastic changes, occurring in the spinal cord and also in the brain.
An important plastic change in the spinal cord could be the progressive reduction of postactivation depression due to limb immobilization.
As well as hyperexcitable stretch reflexes, secondary soft tissue changes in the paretic limbs enhance muscle resistance to passive displacements.
Therefore, in patients with UMNS, hypertonia can be divided into two components: hypertonia mediated by the stretch reflex, which corresponds to spasticity, and hypertonia due to soft tissue changes, which is often referred as nonreflex hypertonia or intrinsic hypertonia.
Compelling evidences state that limb mobilisation in patients with UMNS is essential to prevent and treat both spasticity and intrinsic hypertonia.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Trompetto, Carlo& Marinelli, Lucio& Mori, Laura& Pelosin, Elisa& Currà, Antonio& Molfetta, Luigi…[et al.]. 2014. Pathophysiology of Spasticity: Implications for Neurorehabilitation. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1034439
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Trompetto, Carlo…[et al.]. Pathophysiology of Spasticity: Implications for Neurorehabilitation. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1034439
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Trompetto, Carlo& Marinelli, Lucio& Mori, Laura& Pelosin, Elisa& Currà, Antonio& Molfetta, Luigi…[et al.]. Pathophysiology of Spasticity: Implications for Neurorehabilitation. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1034439
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1034439
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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