Malignant Trigeminal Nerve Sheath Tumor and Anaplastic Astrocytoma Collision Tumor with High Proliferative Activity and Tumor Suppressor P53 Expression
المؤلفون المشاركون
Baeesa, Saleh S.
Kurdi, Maher
Al-Ardati, Hosam
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-10-15
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
The synchronous development of two primary brain tumors of distinct cell of origin in close proximity or in contact with each other is extremely rare.
We present the first case of collision tumor with two histological distinct tumors.
Case Presentation.
A 54-year-old woman presented with progressive atypical left facial pain and numbness for 8 months.
MRI of the brain showed left middle cranial fossa heterogeneous mass extending into the infratemporal fossa.
At surgery, a distinct but intermingled intra- and extradural tumor was demonstrated which was completely removed through left orbitozygomatic-temporal craniotomy.
Histopathological examination showed that the tumor had two distinct components: malignant nerve sheath tumor of the trigeminal nerve and temporal lobe anaplastic astrocytoma.
Proliferative activity and expressed tumor protein 53 (TP53) gene mutations were demonstrated in both tumors.
Conclusions.
We describe the first case of malignant trigeminal nerve sheath tumor (MTNST) and anaplastic astrocytoma in collision and discuss the possible hypothesis of this rare occurrence.
We propose that MTNST, with TP53 mutation, have participated in the formation of anaplastic astrocytoma, or vice versa.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kurdi, Maher& Al-Ardati, Hosam& Baeesa, Saleh S.. 2014. Malignant Trigeminal Nerve Sheath Tumor and Anaplastic Astrocytoma Collision Tumor with High Proliferative Activity and Tumor Suppressor P53 Expression. Case Reports in Pathology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1034906
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kurdi, Maher…[et al.]. Malignant Trigeminal Nerve Sheath Tumor and Anaplastic Astrocytoma Collision Tumor with High Proliferative Activity and Tumor Suppressor P53 Expression. Case Reports in Pathology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1034906
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kurdi, Maher& Al-Ardati, Hosam& Baeesa, Saleh S.. Malignant Trigeminal Nerve Sheath Tumor and Anaplastic Astrocytoma Collision Tumor with High Proliferative Activity and Tumor Suppressor P53 Expression. Case Reports in Pathology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1034906
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1034906
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر