Six-Digit CPK and Mildly Affected Renal Function in McArdle Disease

الملخص EN

A previously healthy, white 12-year-old girl presented with diffuse body aches and poor perfusion.

She developed severe respiratory failure and marked rhabdomyolysis and was mechanically ventilated.

Although her CPK peaked at 500,000 IU/L, her renal function was mildly affected and her creatinine did not exceed the 0.8 mg/dL.

The rhabdomyolysis was gradually resolved following aggressive fluid hydration.

The patient did not require dialysis and made a complete recovery.

Genetic studies revealed the diagnosis of McArdle disease.