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Effects of Brown Seaweed (Sargassum polycystum) Extracts on Kidney, Liver, and Pancreas of Type 2 Diabetic Rat Model
المؤلفون المشاركون
Yong Meng, Goh
Ebrahimi, Mahdi
Hair-Bejo, Mohd
Motshakeri, Mahsa
Mohamed, Suhaila
Othman, Hemn Hassan
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-01-08
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
The edible seaweed Sargassum polycystum (SP) is traditionally used against several human diseases.
This investigation evaluated the effects of two dietary doses of SP ethanolic and aqueous extracts on the pancreatic, hepatic, and renal morphology of type 2 diabetic rats (T2DM).
T2DM was induced by feeding rats on high calorie diet followed by a low dose streptozotocin.
Changes in the diabetic rat organs in SP treated groups with different doses of extracts were compared with normal rats, diabetic control rats, and metformin treated rats.
After 22 days of treatment, the pathological lesions of the livers and kidneys in the diabetic rats were quantitatively and qualitatively alleviated ( P < 0.05 ) by both the SP extracts at 150 mg/kg body weight and by metformin.
All the treated diabetic groups revealed marked improvement in the histopathology of the pancreas compared with the control diabetic group.
Oral administration of 300 mg/kg body weight of aqueous and ethanolic extracts of SP and metformin revealed pancreas protective or restorative effects.
The seaweed extracts at 150 mg/kg body weight reduced the liver and kidney damages in the diabetic rats and may exert tissue repair or restoration of the pancreatic islets in experimentally induced diabetes to produce the beneficial homeostatic effects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Motshakeri, Mahsa& Ebrahimi, Mahdi& Yong Meng, Goh& Othman, Hemn Hassan& Hair-Bejo, Mohd& Mohamed, Suhaila. 2014. Effects of Brown Seaweed (Sargassum polycystum) Extracts on Kidney, Liver, and Pancreas of Type 2 Diabetic Rat Model. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1035175
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Motshakeri, Mahsa…[et al.]. Effects of Brown Seaweed (Sargassum polycystum) Extracts on Kidney, Liver, and Pancreas of Type 2 Diabetic Rat Model. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1035175
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Motshakeri, Mahsa& Ebrahimi, Mahdi& Yong Meng, Goh& Othman, Hemn Hassan& Hair-Bejo, Mohd& Mohamed, Suhaila. Effects of Brown Seaweed (Sargassum polycystum) Extracts on Kidney, Liver, and Pancreas of Type 2 Diabetic Rat Model. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1035175
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1035175
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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