Systematic Analysis of the Multiple Bioactivities of Green Tea through a Network Pharmacology Approach
المؤلفون المشاركون
Zhang, Shoude
Shan, Lei
Li, Qiao
Wang, Xia
Li, Shiliang
Zhang, Yuan
Fu, Jianjun
Zhang, Weidong
Liu, Xiaofeng
Li, Honglin
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-11-30
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
During the past decades, a number of studies have demonstrated multiple beneficial health effects of green tea.
Polyphenolics are the most biologically active components of green tea.
Many targets can be targeted or affected by polyphenolics.
In this study, we excavated all of the targets of green tea polyphenolics (GTPs) though literature mining and target calculation and analyzed the multiple pharmacology actions of green tea comprehensively through a network pharmacology approach.
In the end, a total of 200 Homo sapiens targets were identified for fifteen GTPs.
These targets were classified into six groups according to their related disease, which included cancer, diabetes, neurodegenerative disease, cardiovascular disease, muscular disease, and inflammation.
Moreover, these targets mapped into 143 KEGG pathways, 26 of which were more enriched, as determined though pathway enrichment analysis and target-pathway network analysis.
Among the identified pathways, 20 pathways were selected for analyzing the mechanisms of green tea in these diseases.
Overall, this study systematically illustrated the mechanisms of the pleiotropic activity of green tea by analyzing the corresponding “drug-target-pathway-disease” interaction network.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Shoude& Shan, Lei& Li, Qiao& Wang, Xia& Li, Shiliang& Zhang, Yuan…[et al.]. 2014. Systematic Analysis of the Multiple Bioactivities of Green Tea through a Network Pharmacology Approach. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1035248
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Shoude…[et al.]. Systematic Analysis of the Multiple Bioactivities of Green Tea through a Network Pharmacology Approach. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1035248
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Shoude& Shan, Lei& Li, Qiao& Wang, Xia& Li, Shiliang& Zhang, Yuan…[et al.]. Systematic Analysis of the Multiple Bioactivities of Green Tea through a Network Pharmacology Approach. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1035248
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1035248
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر