Genus Caulophyllum: An Overview of Chemistry and Bioactivity

الملخص EN

Recently, some promising advances have been achieved in understanding the chemistry, pharmacology, and action mechanisms of constituents from genus Caulophyllum.

Despite this, there is to date no systematic review of those of genus Caulophyllum.

This review covers naturally occurring alkaloids and saponins and those resulting from synthetic novel taspine derivatives.

The paper further discussed several aspects of this genus, including pharmacological properties, mechanisms of action, pharmacokinetics, and cell membrane chromatography for activity screening.

The aim of this paper is to provide a point of reference for pharmaceutical researchers to develop new drugs from constituents of Caulophyllum plants.