![](/images/graphics-bg.png)
Adverse Drug Reactions and Expected Effects to Therapy with Subcutaneous Mistletoe Extracts (Viscum album L.) in Cancer Patients
المؤلفون المشاركون
Matthes, H.
Steele, Megan L.
Axtner, Jan
Happe, Antje
Kröz, Matthias
Schad, Friedemann
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-01-16
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
In Europe, mistletoe extracts are widely used as a complementary cancer therapy.
We assessed the safety of subcutaneous mistletoe as a conjunctive therapy in cancer patients within an anthroposophic medicine setting in Germany.
Methods.
A multicentre, observational study was performed within the Network Oncology.
Suspected mistletoe adverse drug reactions (ADRs) were described by frequency, causality, severity, and seriousness.
Potential risk factors, dose relationships and drug-drug interactions were investigated.
Results.
Of 1923 cancer patients treated with subcutaneous mistletoe extracts, 283 patients (14.7%) reported 427 expected effects (local reactions <5 cm and increased body temperature <38°C).
ADRs were documented in 162 (8.4%) patients who reported a total of 264 events.
ADRs were mild (50.8%), moderate (45.1%), or severe (4.2%).
All were nonserious.
Logistic regression analysis revealed that expected effects were more common in females, while immunoreactivity decreased with increasing age and tumour stage.
No risk factors were identified for ADRs.
ADR frequency increased as mistletoe dose increased, while fewer ADRs occurred during mistletoe therapy received concurrent with conventional therapies.
Conclusion.
The results of this study indicate that mistletoe therapy is safe.
ADRs were mostly mild to moderate in intensity and appear to be dose-related and explained by the immune-stimulating, pharmacological activity of mistletoe.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Steele, Megan L.& Axtner, Jan& Happe, Antje& Kröz, Matthias& Matthes, H.& Schad, Friedemann. 2014. Adverse Drug Reactions and Expected Effects to Therapy with Subcutaneous Mistletoe Extracts (Viscum album L.) in Cancer Patients. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1035350
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Steele, Megan L.…[et al.]. Adverse Drug Reactions and Expected Effects to Therapy with Subcutaneous Mistletoe Extracts (Viscum album L.) in Cancer Patients. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1035350
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Steele, Megan L.& Axtner, Jan& Happe, Antje& Kröz, Matthias& Matthes, H.& Schad, Friedemann. Adverse Drug Reactions and Expected Effects to Therapy with Subcutaneous Mistletoe Extracts (Viscum album L.) in Cancer Patients. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1035350
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1035350
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)