Safety of Intravenous Application of Mistletoe (Viscum album L.) Preparations in Oncology: An Observational Study
المؤلفون المشاركون
Matthes, H.
Steele, Megan L.
Axtner, Jan
Happe, Antje
Kröz, Matthias
Schad, Friedemann
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-15
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
Traditional mistletoe therapy in cancer patients involves subcutaneous applications of Viscum album L.
preparations, with doses slowly increasing based on patient responses.
Intravenous infusion of high doses may improve therapeutic outcomes and is becoming more common.
Little is known about the safety of this “off-label” application of mistletoe.
Methods.
An observational study was performed within the Network Oncology.
Treatment with intravenous mistletoe applications is described.
The frequency of adverse drug reactions (ADRs) to intravenous mistletoe applications was calculated and compared to ADR data from a study on subcutaneous applications.
Results.
Of 475 cancer patients who received intravenous infusions of Helixor, Abnoba viscum, or Iscador mistletoe preparations, 22 patients (4.6%) reported 32 ADRs of mild (59.4%) or moderate severity (40.6%).
No serious ADRs occurred.
ADRs were more frequently reported to i.v.
mistletoe administered alone (4.3%), versus prior to chemotherapy (1.6%).
ADR frequency differed with respect to preparation type, with Iscador preparations showing a higher relative frequency, compared to Abnoba viscum and Helixor.
Overall, patients were almost two times less likely to experience an ADR to intravenous compared to subcutaneous application of mistletoe.
Conclusion.
Intravenous mistletoe therapy was found to be safe and prospective studies for efficacy are recommended.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Steele, Megan L.& Axtner, Jan& Happe, Antje& Kröz, Matthias& Matthes, H.& Schad, Friedemann. 2014. Safety of Intravenous Application of Mistletoe (Viscum album L.) Preparations in Oncology: An Observational Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1035826
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Steele, Megan L.…[et al.]. Safety of Intravenous Application of Mistletoe (Viscum album L.) Preparations in Oncology: An Observational Study. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1035826
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Steele, Megan L.& Axtner, Jan& Happe, Antje& Kröz, Matthias& Matthes, H.& Schad, Friedemann. Safety of Intravenous Application of Mistletoe (Viscum album L.) Preparations in Oncology: An Observational Study. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1035826
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1035826
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر