The Association between Apolipoprotein E Gene Polymorphism and Mild Cognitive Impairment among Different Ethnic Minority Groups in China
المؤلفون المشاركون
Rong, Ye
Wang, ZhiZhong
Liu, Lan
Ma, Wanrui
المصدر
International Journal of Alzheimer's Disease
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-05
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
The association, in different ethnic groups, of apolipoprotein E (apoE) gene polymorphism with mild cognitive impairment (MCI) has been unclear.
Few studies have examined the association in Chinese minorities.
The current study explores the association between apoE gene polymorphism and MCI in one of the biggest ethnic groups—the Hui—and compares it with the Han.
The Minimental State Exam, Activities of Daily Living Scale, and Geriatric Depression Scale were administered to 306 ethnic Hui and 618 ethnic Han people aged ≥55 years.
ApoE genotypes were determined using the high resolution melting curve method.
The distribution of the apoE genotype and the frequency of alleles ε2, ε3, and ε4 were similar in the Hui and Han groups.
In analyses adjusted for age, gender, and education level, the ε4 allele was a risk factor for MCI in both the Hui group (OR=2.61, 95% CI: 1.02–6.66) and the Han group (OR=2.36, 95% CI: 1.19–4.67), but the apoE ε2 allele was protective for MCI only in the Han group (OR=0.48, 95% CI: 0.38–0.88).
The association of some apoE genotypes with MCI may differ in different ethnic groups in China.
Further studies are needed to explore this effect among different populations.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, ZhiZhong& Ma, Wanrui& Rong, Ye& Liu, Lan. 2014. The Association between Apolipoprotein E Gene Polymorphism and Mild Cognitive Impairment among Different Ethnic Minority Groups in China. International Journal of Alzheimer's Disease،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1035937
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, ZhiZhong…[et al.]. The Association between Apolipoprotein E Gene Polymorphism and Mild Cognitive Impairment among Different Ethnic Minority Groups in China. International Journal of Alzheimer's Disease No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1035937
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, ZhiZhong& Ma, Wanrui& Rong, Ye& Liu, Lan. The Association between Apolipoprotein E Gene Polymorphism and Mild Cognitive Impairment among Different Ethnic Minority Groups in China. International Journal of Alzheimer's Disease. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1035937
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1035937
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر