Sentinel Node Biopsy Alone versus Completion Axillary Node Dissection in Node Positive Breast Cancer: Systematic Review and Meta-Analysis
المؤلفون المشاركون
Ram, Rachna
Singh, Jasprit
McCaig, Eddie
المصدر
International Journal of Breast Cancer
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-10-14
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Introduction.
There has been recent interest in validity of completion axillary node dissection after a positive sentinel node.
This systematic review aims to ascertain if sentinel lymph node dissection alone was noninferior to axillary lymph node dissection for breast cancer patients who have a positive sentinel node.
Method.
A systematic review of the electronic databases Embase, MEDLINE, and Cochrane Register of Controlled Trials was carried out.
Only randomised trials that had patients with positive sentinel node as the study sample were included in the meta-analysis using the reported hazard ratios with a fixed effect model.
Results.
Three randomised controlled trials and five retrospective studies were identified.
The pooled effect for overall survival was HR 0.94, 95% CI [0.79, 1.19], and for disease free survival was HR 0.83, 95% CI [0.60, 1.14].
The reported rates for locoregional recurrence were similar in both groups.
The surgical morbidity was found to be significantly more in patients who had underwent axillary dissection.
Conclusion.
Amongst patients with micrometastasis in the sentinel node, no further axillary dissection is necessary.
For patients with macrometastasis in the sentinel node, it is reasonable to consider omitting axillary dissection to avoid the morbidity of the procedure.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ram, Rachna& Singh, Jasprit& McCaig, Eddie. 2014. Sentinel Node Biopsy Alone versus Completion Axillary Node Dissection in Node Positive Breast Cancer: Systematic Review and Meta-Analysis. International Journal of Breast Cancer،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1036303
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ram, Rachna…[et al.]. Sentinel Node Biopsy Alone versus Completion Axillary Node Dissection in Node Positive Breast Cancer: Systematic Review and Meta-Analysis. International Journal of Breast Cancer No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1036303
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ram, Rachna& Singh, Jasprit& McCaig, Eddie. Sentinel Node Biopsy Alone versus Completion Axillary Node Dissection in Node Positive Breast Cancer: Systematic Review and Meta-Analysis. International Journal of Breast Cancer. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1036303
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1036303
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر