Meta-Analysis: Overweight, Obesity, and Parkinson's Disease
المؤلفون المشاركون
Chen, Jinhu
Guan, Zhenlong
Wang, Liqin
Song, Guangyao
Ma, Boqing
Wang, Yanqin
المصدر
International Journal of Endocrinology
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-05
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
Parkinson's disease (PD) is a severe neurological disease and its risk factors remain largely unknown.
A meta-analysis was carried out to investigate the relationship of overweight and obesity with PD.
Methods.
We used PubMed, EMBASE, and the Chinese National Knowledge Infrastructure (CNKI) databases to identify studies of associations between overweight/obesity and PD.
Overweight, obesity, and PD were used as keywords, and published works were retrieved until September 30, 2013.
The extracted data were classified ( BMI ≥ 30 , 25 ≤ BMI < 30 , and BMI < 25 ) according to BMI values and analyzed using RevMan5.2 and Stata11.0.
Results.
Four cohort studies and three case-control studies were used to evaluate the association between overweight/obesity and PD, including 2857 PD patients and 5, 683, 939 cases of non-PD controls.
There was a statistically significant difference between 25 ≤ BMI < 30 and BMI < 25 in the cohort study ( R R = 1.17 , 95% CI , 1.03–1.32, P = 0.03 ), but there was no difference between BMI ≥ 30 and BMI < 25 or BMI ≥ 30 and 25 ≤ BMI < 30 , where the respective R R was 1.16 and 0.84; the respective 95% CI was 0.67–2.01 and 0.61–1.15, respectively, and the P values were 0.60 and 0.28, respectively.
Case-control studies showed that there was no statistical difference between any two groups.
Conclusion.
Meta-analysis showed that overweight might be a potential risk factor of PD.
Demonstration of a causal role of overweight/obesity in PD development could have important therapeutic implications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Jinhu& Guan, Zhenlong& Wang, Liqin& Song, Guangyao& Ma, Boqing& Wang, Yanqin. 2014. Meta-Analysis: Overweight, Obesity, and Parkinson's Disease. International Journal of Endocrinology،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1036432
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Jinhu…[et al.]. Meta-Analysis: Overweight, Obesity, and Parkinson's Disease. International Journal of Endocrinology No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1036432
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Jinhu& Guan, Zhenlong& Wang, Liqin& Song, Guangyao& Ma, Boqing& Wang, Yanqin. Meta-Analysis: Overweight, Obesity, and Parkinson's Disease. International Journal of Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1036432
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1036432
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر