Adrenocortical Production Is Associated with Higher Levels of Luteinizing Hormone in Nonobese Women with Polycystic Ovary Syndrome
المؤلفون المشاركون
Tufik, Sergio
Tock, Luciana
Carneiro, Gláucia
Pereira, Andrea Z.
Zanella, Maria Teresa
المصدر
International Journal of Endocrinology
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-07
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
Insulin resistance (IR) and ovarian and adrenal hyperandrogenism are a common finding in women with polycystic ovary syndrome (PCOS).
The aim of the present study was to access possible differences in insulin resistance, gonadotropins, and androgens production in obese and nonobese PCOS women.
Study Design.
We studied 37 PCOS women (16 nonobese and 21 obese) and 18 nonobese controls.
Fasting glucose, insulin, androgens, and gonadotropins levels were determined.
Salivary cortisol was measured basal and in the morning after dexamethasone (DEX) 0.25 mg.
Results.
Nonobese PCOS women showed higher basal salivary cortisol and serum dehydroepiandrosterone sulfate and luteinizing hormone (LH) levels than controls and obese PCOS.
These hormones levels did not differ between the obese and control groups.
After DEX administration no differences were found between the three groups.
In PCOS women, salivary cortisol levels showed negative correlation with BMI ( r = - 0.52 ; P = 0.001 ) and insulin ( r = - 0.47 ; P = 0.003 ) and positive correlation with LH ( r = 0.40 ; P = 0.016 ).
Conclusion.
Our results show an increased adrenocortical production in nonobese PCOS women, not related to IR and associated with a normal hypothalamic-pituitary-adrenal suppression.
Higher LH levels might be involved in this event.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tock, Luciana& Carneiro, Gláucia& Pereira, Andrea Z.& Tufik, Sergio& Zanella, Maria Teresa. 2014. Adrenocortical Production Is Associated with Higher Levels of Luteinizing Hormone in Nonobese Women with Polycystic Ovary Syndrome. International Journal of Endocrinology،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1036542
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tock, Luciana…[et al.]. Adrenocortical Production Is Associated with Higher Levels of Luteinizing Hormone in Nonobese Women with Polycystic Ovary Syndrome. International Journal of Endocrinology No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1036542
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tock, Luciana& Carneiro, Gláucia& Pereira, Andrea Z.& Tufik, Sergio& Zanella, Maria Teresa. Adrenocortical Production Is Associated with Higher Levels of Luteinizing Hormone in Nonobese Women with Polycystic Ovary Syndrome. International Journal of Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1036542
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1036542
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر