Sustained Liver Glucose Release in Response to Adrenaline Can Improve Hypoglycaemic Episodes in Rats under Food Restriction Subjected to Acute Exercise
المؤلفون المشاركون
Godoi-Gazola, Vilma Aparecida Ferreira de
Babata, Lucas K. R.
Garcia, Rosângela F.
Peicher, Márcia V.
Diaz Pedrosa, Maria Montserrat
المصدر
International Journal of Endocrinology
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-27
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
As the liver is important for blood glucose regulation, this study aimed at relating liver glucose release stimulated by glucagon and adrenaline to in vivo episodes of hypoglycaemia.
Methods.
The blood glucose profile during an episode of insulin-induced hypoglycaemia in exercised and nonexercised male Wistar control (GC) and food-restricted (GR, 50%) rats and liver glucose release stimulated by glucagon and adrenaline were investigated.
Results.
In the GR, the hypoglycaemic episodes showed severe decreases in blood glucose, persistent hypoglycaemia, and less complete glycaemic recovery.
An exercise session prior to the episode of hypoglycaemia raised the basal blood glucose, reduced the magnitude of the hypoglycaemia, and improved the recovery of blood glucose.
In fed animals of both groups, liver glucose release was activated by glucagon and adrenaline.
In fasted GR rats, liver glycogenolysis activated by glucagon was impaired, despite a significant basal glycogenolysis, while an adrenaline-stimulated liver glucose release was recorded.
Conclusions.
The lack of liver response to glucagon in the GR rats could be partially responsible for the more severe episodes of hypoglycaemia observed in vivo in nonexercised animals.
The preserved liver response to adrenaline can partially account for the less severe hypoglycaemia in the food-restricted animals after acute exercise.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Babata, Lucas K. R.& Diaz Pedrosa, Maria Montserrat& Garcia, Rosângela F.& Peicher, Márcia V.& Godoi-Gazola, Vilma Aparecida Ferreira de. 2014. Sustained Liver Glucose Release in Response to Adrenaline Can Improve Hypoglycaemic Episodes in Rats under Food Restriction Subjected to Acute Exercise. International Journal of Endocrinology،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1036634
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Babata, Lucas K. R.…[et al.]. Sustained Liver Glucose Release in Response to Adrenaline Can Improve Hypoglycaemic Episodes in Rats under Food Restriction Subjected to Acute Exercise. International Journal of Endocrinology No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1036634
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Babata, Lucas K. R.& Diaz Pedrosa, Maria Montserrat& Garcia, Rosângela F.& Peicher, Márcia V.& Godoi-Gazola, Vilma Aparecida Ferreira de. Sustained Liver Glucose Release in Response to Adrenaline Can Improve Hypoglycaemic Episodes in Rats under Food Restriction Subjected to Acute Exercise. International Journal of Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1036634
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1036634
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر