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Prognostic Importance of Fibroblast Growth Factor-23 in Dialysis Patients
المؤلفون المشاركون
Gedikbasi, Asuman
Akalin, Nilgül
Okuturlar, Yıldız
Harmankaya, Özlem
Sezıklı, Selçuk
Koçak Yücel, Sibel
المصدر
International Journal of Nephrology
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-09-10
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Introduction.
In this study, we aimed to demonstrate the correlation of FGF-23 levels with bone-mineral metabolism, anemia, and the treatment in dialysis patients.
Methods.
Eighty-nine patients with similar age, gender, dialysis duration, and dialysis adequacy who were receiving hemodialysis replacement therapy for at least 6 months were included in the study.
Serum iron, iron binding capacity, ferritin, hemoglobin (Hb), hematocrit (Htc), calcium (Ca), phosphorus (P), intact parathormone (iPTH), and FGF-23 levels were studied.
In addition, active vitamin D and phosphate binders calcimimetic therapies that patients have received in the last 6 months were recorded.
Results.
It was determined that there was a positive correlation between serum FGF-23 values and PTH values (P<0,01) and Ca*P values (P<0,01).
A positive correlation was found between serum FGF-23 values and Ca values at a rate of 24,6% (P<0,05) and between P values at a rate of 59,1% (P<0,01).
A positive correlation was determined between serum FGF-23 values and hemoglobin (Hb) values (P<0,05) and hematocrit (Htc) values (P<0,05).
In multivariate analysis, no significant correlation was found between serum FGF-23 levels and Hb and Htc.
Conclusion.
The effects of high serum FGF-23 levels on different parameters may be correlated with the development of refractory secondary hyperparathyroidism.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Akalin, Nilgül& Okuturlar, Yıldız& Harmankaya, Özlem& Gedikbasi, Asuman& Sezıklı, Selçuk& Koçak Yücel, Sibel. 2014. Prognostic Importance of Fibroblast Growth Factor-23 in Dialysis Patients. International Journal of Nephrology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1036752
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Akalin, Nilgül…[et al.]. Prognostic Importance of Fibroblast Growth Factor-23 in Dialysis Patients. International Journal of Nephrology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1036752
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Akalin, Nilgül& Okuturlar, Yıldız& Harmankaya, Özlem& Gedikbasi, Asuman& Sezıklı, Selçuk& Koçak Yücel, Sibel. Prognostic Importance of Fibroblast Growth Factor-23 in Dialysis Patients. International Journal of Nephrology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1036752
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1036752
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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