The Application of Polysaccharide Biocomposites to Repair Cartilage Defects

المؤلفون المشاركون

Gao, Hongyang
Zhao, Feng
He, Wei
Yan, Yueling
Zhang, Hongjuan
Zhang, Guoping
Tian, Dehu

المصدر

International Journal of Polymer Science

العدد

المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2014-04-17

دولة النشر

مصر

عدد الصفحات

9

التخصصات الرئيسية

الفيزياء

الملخص EN

Owing to own nature of articular cartilage, it almost has no self-healing ability once damaged.

Despite lots of restore technologies having been raised in the past decades, no repair technology has smoothly substituted for damaged cartilage using regenerated cartilage tissue.

The approach of tissue engineering opens a door to successfully repairing articular cartilage defects.

For instance, grafting of isolated chondrocytes has huge clinical potential for restoration of cartilage tissue and cure of chondral injury.

In this paper, SD rats are used as subjects in the experiments, and they are classified into three groups: natural repair (group A), hyaluronic acid repair (group B), and polysaccharide biocomposites repair (hyaluronic acid hydrogel containing chondrocytes, group C).

Through the observation of effects of repairing articular cartilage defects, we concluded that cartilage repair effect of polysaccharide biocomposites was the best at every time point, and then the second best was hyaluronic acid repair; both of them were better than natural repair.

Polysaccharide biocomposites have good biodegradability and high histocompatibility and promote chondrocytes survival, reproduction, and spliting.

Moreover, polysaccharide biocomposites could not only provide the porous network structure but also carry chondrocytes.

Consequently hyaluronic acid-based polysaccharide biocomposites are considered to be an ideal biological material for repairing articular cartilage.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Zhao, Feng& He, Wei& Yan, Yueling& Zhang, Hongjuan& Zhang, Guoping& Tian, Dehu…[et al.]. 2014. The Application of Polysaccharide Biocomposites to Repair Cartilage Defects. International Journal of Polymer Science،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1037562

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Zhao, Feng…[et al.]. The Application of Polysaccharide Biocomposites to Repair Cartilage Defects. International Journal of Polymer Science No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1037562

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Zhao, Feng& He, Wei& Yan, Yueling& Zhang, Hongjuan& Zhang, Guoping& Tian, Dehu…[et al.]. The Application of Polysaccharide Biocomposites to Repair Cartilage Defects. International Journal of Polymer Science. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1037562

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1037562