Cardioprotective Effect of the Aqueous Extract of Lavender Flower against Myocardial IschemiaReperfusion Injury
المؤلفون المشاركون
Wang, Dong
Guo, Xin
Zhou, Mingjie
Han, Jichun
Han, Bo
Sun, Xiling
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-29
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
This study was conducted to evaluate the cardioprotective property of the aqueous extract of lavender flower (LFAE).
The myocardial ischemia/reperfusion (I/R) injury of rat was prepared by Langendorff retrograde perfusion technology.
The heart was preperfused with K-H solution containing LFAE for 10 min before 20 minutes global ischemia, and then the reperfusion with K-H solution was conducted for 45 min.
The left ventricular developed pressure (LVDP) and the maximum up/downrate of left ventricular pressure (± d p / d t max ) were recorded by physiological recorder as the myocardial function and the myocardial infarct size was detected by TTC staining.
Lactate dehydrogenase (LDH) and creatine kinase (CK) activities in the effluent were measured to determine the myocardial injury degree.
The superoxide anion dismutase (SOD) and malondialdehyde (MDA) in myocardial tissue were detected to determine the oxidative stress degree.
The results showed that the pretreatment with LFAE significantly decreased the myocardial infarct size and also decreased the LDH, CK activities, and MDA level, while it increased the LVDP, ± d p / d t max , SOD activities, and the coronary artery flow.
Our findings indicated that LFAE could provide protection for heart against the I/R injury which may be related to the improvement of myocardial oxidative stress states.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Dong& Guo, Xin& Zhou, Mingjie& Han, Jichun& Han, Bo& Sun, Xiling. 2014. Cardioprotective Effect of the Aqueous Extract of Lavender Flower against Myocardial IschemiaReperfusion Injury. Journal of Chemistry،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1039965
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Dong…[et al.]. Cardioprotective Effect of the Aqueous Extract of Lavender Flower against Myocardial IschemiaReperfusion Injury. Journal of Chemistry No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1039965
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Dong& Guo, Xin& Zhou, Mingjie& Han, Jichun& Han, Bo& Sun, Xiling. Cardioprotective Effect of the Aqueous Extract of Lavender Flower against Myocardial IschemiaReperfusion Injury. Journal of Chemistry. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1039965
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1039965
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر