Decreased Plasma Nesfatin-1 Level Is Related to the Thyroid Dysfunction in Patients with Type 2 Diabetes Mellitus
المؤلفون المشاركون
Liu, Fupeng
Yang, Qing
Gao, Ning
Liu, Fangfang
Chen, Shaohua
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-04
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Aims.
Thyroid dysfunction is frequently observed in patients with type 2 diabetes mellitus (T2DM), but the underlying mechanism is still poorly understood.
The present study aimed to investigate whether nesfatin-1 played a role in the thyroid dysfunction in patients with T2DM.
Methods.
55 euthyroid patients were enrolled in this study including 30 patients with T2DM and 25 patients with impaired glucose regulation (IGR).
30 age-matched healthy people were also included as the control.
The plasma levels of nesfatin-1, thyrotropin (TSH), and glycosylated hemoglobin (HbA1c) as well as the body mass index (BMI) were comparatively analyzed among the three groups.
Results.
The nesfatin-1 was significantly lower in patients with T2DM than in patients with IGR and in the control.
On the contrary, the TSH level was significantly higher in patients with T2DM than in patients with IGR and in the control.
Simple regression analysis showed that the plasma nesfatin-1 was negatively correlated with the TSH and HbA1c levels and positively correlated with the BMI.
With multiple stepwise regression analysis, the nesfatin-1 remained to be independently correlated with the TSH, BMI, and HbA1c.
Conclusions.
The study was suggesting a role of nesfatin-1 in thyroid dysfunction in patients with T2DM.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Fupeng& Yang, Qing& Gao, Ning& Liu, Fangfang& Chen, Shaohua. 2014. Decreased Plasma Nesfatin-1 Level Is Related to the Thyroid Dysfunction in Patients with Type 2 Diabetes Mellitus. Journal of Diabetes Research،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1040223
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Fupeng…[et al.]. Decreased Plasma Nesfatin-1 Level Is Related to the Thyroid Dysfunction in Patients with Type 2 Diabetes Mellitus. Journal of Diabetes Research No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1040223
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Fupeng& Yang, Qing& Gao, Ning& Liu, Fangfang& Chen, Shaohua. Decreased Plasma Nesfatin-1 Level Is Related to the Thyroid Dysfunction in Patients with Type 2 Diabetes Mellitus. Journal of Diabetes Research. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1040223
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1040223
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر