Ocular Inflammation in Uveal Tract in Aged Obese Type 2 Diabetic Rats (Spontaneously Diabetic Torii Fatty Rats)
المؤلفون المشاركون
Kakehashi, Akihiro
Kakimoto, Kochi
Yasui, Yuzo
Toyoda, Kaoru
Shoda, Toshiyuki
Ohta, Takeshi
Sasase, Tomohiko
Kemmochi, Yusuke
Miyajima, Katsuhiro
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-09-14
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
We report uveitis observed in an obese type 2 diabetes rat model, Spontaneously Diabetic Torii Leprfa (SDT fatty) rats aged over 50 weeks.
The eyes of SDT fatty rats (16 animals: 7 males and 9 females with 50 or 60 weeks of age) were examined histopathologically.
Infiltration of inflammatory cells in the uveal tract was observed in 13 of 16 animals.
One female showed severe inflammation affecting the entire uveal tract including the iris, ciliary body, and choroid with a variety of inflammatory cells (neutrophils, lymphocytes, and macrophages).
Those changes clinically mimic the findings of diabetic iridocyclitis in diabetic patients.
Uveitis associated with diabetes can occur in diabetic patients but the pathogenesis still remains unknown.
Since increased extramedullary hematopoiesis in the spleen and abscess in the genital and lower urinary tracts were observed in some SDT fatty rats, increased susceptibility to infection, prolongation of inflammatory states, and disorders of the immune system were considered to be possible factors of the uveitis in aged SDT fatty rats.
There have been few reports on how diabetes has influence on the development of uveitis associated with bacterial infection.
The SDT fatty rat can be an animal model to investigate diabetes-associated uveitis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kemmochi, Yusuke& Miyajima, Katsuhiro& Ohta, Takeshi& Sasase, Tomohiko& Yasui, Yuzo& Toyoda, Kaoru…[et al.]. 2014. Ocular Inflammation in Uveal Tract in Aged Obese Type 2 Diabetic Rats (Spontaneously Diabetic Torii Fatty Rats). Journal of Diabetes Research،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1040320
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kemmochi, Yusuke…[et al.]. Ocular Inflammation in Uveal Tract in Aged Obese Type 2 Diabetic Rats (Spontaneously Diabetic Torii Fatty Rats). Journal of Diabetes Research No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1040320
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kemmochi, Yusuke& Miyajima, Katsuhiro& Ohta, Takeshi& Sasase, Tomohiko& Yasui, Yuzo& Toyoda, Kaoru…[et al.]. Ocular Inflammation in Uveal Tract in Aged Obese Type 2 Diabetic Rats (Spontaneously Diabetic Torii Fatty Rats). Journal of Diabetes Research. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1040320
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1040320
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر