The Association between Serum Uric Acid and Residual β-Cell Function in Type 2 Diabetes
المؤلفون المشاركون
Yang, Tao
Fu, Qi
Zhang, Qingqing
Sun, Min
Tang, Wei
Gao, Yuan
Liu, Xuan
Qian, Li
Shan, Shan
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-26
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The aim of this study was to investigate the relationship of serum uric acid (sUA) with residual β-cell function in type 2 diabetes.
Oral glucose tolerance tests (OGTT) were performed on 1021 type 2 diabetes patients.
The ratio of area under curve of insulin to glucose during 0 to 30 min and 0 to 120 min of the OGTT was calculated as indices of insulin secretion function.
The products of insulin secretion indices multiplied by Matsuda insulin sensitivity index were used as disposition indices.
After correlation and multiple linear regression analysis, sUA was significantly associated with insulin secretion and disposition indices in male, female, and total groups adjusted for confounding factors (including metabolic indicators like sex, age, course of the disease, blood glucose, blood pressure, serum lipids, and so on).
Superficially steeper time-dependent decline of insulin secretion function was found in patients with sUA above the median than those below it.
In conclusion, our results suggest an independent positive association between sUA and residual β-cell function in type 2 diabetes.
Patients with higher sUA have greater insulin secretion ability than those with lower sUA at the early stage of disease, but their residual β-cell function seems to decay more rapidly.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tang, Wei& Fu, Qi& Zhang, Qingqing& Sun, Min& Gao, Yuan& Liu, Xuan…[et al.]. 2014. The Association between Serum Uric Acid and Residual β-Cell Function in Type 2 Diabetes. Journal of Diabetes Research،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1040328
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tang, Wei…[et al.]. The Association between Serum Uric Acid and Residual β-Cell Function in Type 2 Diabetes. Journal of Diabetes Research No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1040328
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tang, Wei& Fu, Qi& Zhang, Qingqing& Sun, Min& Gao, Yuan& Liu, Xuan…[et al.]. The Association between Serum Uric Acid and Residual β-Cell Function in Type 2 Diabetes. Journal of Diabetes Research. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1040328
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1040328
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر