Clinical, Laboratory, and Therapeutic Analyses of 21 Patients with Neonatal Thrombosis and Antiphospholipid Antibodies: A Literature Review
المؤلفون المشاركون
Rodrigues, Carlos Ewerton Maia
Peixoto, Marcus Vinicius da Costa
De Carvalho, Jozélio Freire
المصدر
Journal of Immunology Research
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-17
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objectives.
A review of the literature reports neonatal thrombosis and antiphospholipid antibodies cases through a retrospective study that focuses on the pathogenesis and main clinical and laboratory manifestations of this disease.
Methods.
The case reports were selected from PubMed.
The keywords used to search were neonatal, antiphospholipid syndrome, thrombosis, and antiphospholipid antibodies.
References that were published from 1987 to 2013 were reviewed.
Results.
Twenty-one cases of neonatal thrombosis and antiphospholipid antibodies were identified.
Ten children were born preterm (before 37 weeks).
Arterial involvement (17/21) was predominant, of which stroke (12/17) was the most prevalent clinical manifestation.
Anti-cardiolipin antibodies were predominant (13/21) in the antiphospholipid antibody profiles.
Treatments were based on the use of symptomatics such as antiepileptics (8/21), and 6/21 patients received heparin.
There were 4 deaths (4/21); otherwise, the children recovered well, especially the neonates who suffered from strokes (9/12).
Conclusion.
Neonatal thrombosis and antiphospholipid antibodies are rare.
The development of thrombotic manifestations in neonates seems not to be associated exclusively with the aPL, but their etiology may be linked to pre- and perinatal events.
We noted good therapeutic responses, especially in stroke patients, who presented with favorable outcomes in 82% of the cases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Peixoto, Marcus Vinicius da Costa& De Carvalho, Jozélio Freire& Rodrigues, Carlos Ewerton Maia. 2014. Clinical, Laboratory, and Therapeutic Analyses of 21 Patients with Neonatal Thrombosis and Antiphospholipid Antibodies: A Literature Review. Journal of Immunology Research،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1040945
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Peixoto, Marcus Vinicius da Costa…[et al.]. Clinical, Laboratory, and Therapeutic Analyses of 21 Patients with Neonatal Thrombosis and Antiphospholipid Antibodies: A Literature Review. Journal of Immunology Research No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1040945
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Peixoto, Marcus Vinicius da Costa& De Carvalho, Jozélio Freire& Rodrigues, Carlos Ewerton Maia. Clinical, Laboratory, and Therapeutic Analyses of 21 Patients with Neonatal Thrombosis and Antiphospholipid Antibodies: A Literature Review. Journal of Immunology Research. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1040945
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1040945
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر