Association between the −794 (CATT)5–8 MIF Gene Polymorphism and Susceptibility to Acute Coronary Syndrome in a Western Mexican Population
المؤلفون المشاركون
Padilla-Gutiérrez, Jorge Ramón
Flores-Salinas, Hector Enrique
Valle, Yeminia
García-González, Ilian Janet
Valdés-Alvarado, Emmanuel
Sandoval-Pinto, Elena
Valdez-Haro, Angélica
De la Cruz-Mosso, Ulises
Muñoz-Valle, José Francisco
المصدر
Journal of Immunology Research
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-02
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
The macrophage migration inhibitory factor (MIF) is related to the progression of atherosclerosis, which, in turn, is a key factor in the development of acute coronary syndrome (ACS).
MIF has a CATT short tandem repeat (STR) at position −794 that might be involved in its expression rate.
The aim of this study was to investigate the association between the −794 CATT5–8 MIF gene polymorphism and susceptibility to ACS in a western Mexican population.
This research included 200 ACS patients classified according to the criteria of the American College of Cardiology (ACC) and 200 healthy subjects (HS).
The −794 CATT5–8 MIF gene polymorphism was analyzed using a conventional polymerase chain reaction (PCR) technique.
The 6 allele was the most frequent in both groups (ACS: 54% and HS: 57%).
The most common genotypes in ACS patients and HS were 6/7 and 6/6, respectively, and a significant association was found between the 6/7 genotype and susceptibility to ACS (68% versus 47% in ACS and HS, resp., P=0.03).
We conclude that the 6/7 genotype of the MIF −794 CATT5–8 polymorphism is associated with susceptibility to ACS in a western Mexican population.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Valdés-Alvarado, Emmanuel& Muñoz-Valle, José Francisco& Valle, Yeminia& Sandoval-Pinto, Elena& García-González, Ilian Janet& Valdez-Haro, Angélica…[et al.]. 2014. Association between the −794 (CATT)5–8 MIF Gene Polymorphism and Susceptibility to Acute Coronary Syndrome in a Western Mexican Population. Journal of Immunology Research،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1040966
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Valdés-Alvarado, Emmanuel…[et al.]. Association between the −794 (CATT)5–8 MIF Gene Polymorphism and Susceptibility to Acute Coronary Syndrome in a Western Mexican Population. Journal of Immunology Research No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1040966
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Valdés-Alvarado, Emmanuel& Muñoz-Valle, José Francisco& Valle, Yeminia& Sandoval-Pinto, Elena& García-González, Ilian Janet& Valdez-Haro, Angélica…[et al.]. Association between the −794 (CATT)5–8 MIF Gene Polymorphism and Susceptibility to Acute Coronary Syndrome in a Western Mexican Population. Journal of Immunology Research. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1040966
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1040966
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر