Respiratory Syncytial Virus Infections in Infants Affected by Primary Immunodeficiency
المؤلفون المشاركون
Lanari, Marcello
Faldella, Giacomo
Capretti, Maria Grazia
Lazzarotto, Tiziana
Vandini, Silvia
المصدر
Journal of Immunology Research
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-25
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Primary immunodeficiencies are rare inherited disorders that may lead to frequent and often severe acute respiratory infections.
Respiratory syncytial virus (RSV) is one of the most frequent pathogens during early infancy and the infection is more severe in immunocompromised infants than in healthy infants, as a result of impaired T- and B-cell immune response unable to efficaciously neutralize viral replication, with subsequent increased viral shedding and potentially lethal lower respiratory tract infection.
Several authors have reported a severe clinical course after RSV infections in infants and children with primary and acquired immunodeficiencies.
Environmental prophylaxis is essential in order to reduce the infection during the epidemic season in hospitalized immunocompromised infants.
Prophylaxis with palivizumab, a humanized monoclonal antibody against the RSV F protein, is currently recommended in high-risk infants born prematurely, with chronic lung disease or congenital heart disease.
Currently however the prophylaxis is not routinely recommended in infants with primary immunodeficiency, although some authors propose the extension of prophylaxis to this high risk population.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lanari, Marcello& Vandini, Silvia& Capretti, Maria Grazia& Lazzarotto, Tiziana& Faldella, Giacomo. 2014. Respiratory Syncytial Virus Infections in Infants Affected by Primary Immunodeficiency. Journal of Immunology Research،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1041000
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lanari, Marcello…[et al.]. Respiratory Syncytial Virus Infections in Infants Affected by Primary Immunodeficiency. Journal of Immunology Research No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1041000
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lanari, Marcello& Vandini, Silvia& Capretti, Maria Grazia& Lazzarotto, Tiziana& Faldella, Giacomo. Respiratory Syncytial Virus Infections in Infants Affected by Primary Immunodeficiency. Journal of Immunology Research. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1041000
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1041000
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر