![](/images/graphics-bg.png)
Asian Dust Particles Induce Macrophage Inflammatory Responses via Mitogen-Activated Protein Kinase Activation and Reactive Oxygen Species Production
المؤلفون المشاركون
Higashisaka, Kazuma
Fujimura, Maho
Taira, Mayu
Yoshida, Tokuyuki
Tsunoda, Shin-ichi
Baba, Takashi
Yamaguchi, Nobuyasu
Nabeshi, Hiromi
Yoshikawa, Tomoaki
Nasu, Masao
Yoshioka, Yasuo
Tsutsumi, Yasuo
المصدر
Journal of Immunology Research
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-28
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Asian dust is a springtime meteorological phenomenon that originates in the deserts of China and Mongolia.
The dust is carried by prevailing winds across East Asia where it causes serious health problems.
Most of the information available on the impact of Asian dust on human health is based on epidemiological investigations, so from a biological standpoint little is known of its effects.
To clarify the effects of Asian dust on human health, it is essential to assess inflammatory responses to the dust and to evaluate the involvement of these responses in the pathogenesis or aggravation of disease.
Here, we investigated the induction of inflammatory responses by Asian dust particles in macrophages.
Treatment with Asian dust particles induced greater production of inflammatory cytokines interleukin-6 and tumor necrosis factor-α (TNF-α) compared with treatment with soil dust.
Furthermore, a soil dust sample containing only particles ≤10 μm in diameter provoked a greater inflammatory response than soil dust samples containing particles >10 μm.
In addition, Asian dust particles-induced TNF-α production was dependent on endocytosis, the production of reactive oxygen species, and the activation of nuclear factor-κB and mitogen-activated protein kinases.
Together, these results suggest that Asian dust particles induce inflammatory disease through the activation of macrophages.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Higashisaka, Kazuma& Fujimura, Maho& Taira, Mayu& Yoshida, Tokuyuki& Tsunoda, Shin-ichi& Baba, Takashi…[et al.]. 2014. Asian Dust Particles Induce Macrophage Inflammatory Responses via Mitogen-Activated Protein Kinase Activation and Reactive Oxygen Species Production. Journal of Immunology Research،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1041001
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Higashisaka, Kazuma…[et al.]. Asian Dust Particles Induce Macrophage Inflammatory Responses via Mitogen-Activated Protein Kinase Activation and Reactive Oxygen Species Production. Journal of Immunology Research No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1041001
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Higashisaka, Kazuma& Fujimura, Maho& Taira, Mayu& Yoshida, Tokuyuki& Tsunoda, Shin-ichi& Baba, Takashi…[et al.]. Asian Dust Particles Induce Macrophage Inflammatory Responses via Mitogen-Activated Protein Kinase Activation and Reactive Oxygen Species Production. Journal of Immunology Research. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1041001
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1041001
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)