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Release of the Diclofenac Sodium by Nanofibers of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Obtained from Electrospinning and Solution Blow Spinning
المؤلفون المشاركون
Souza, Michelle Andrade
Sakamoto, Karine Yamamura
Mattoso, Luiz H. C.
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-05
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Electrospun fibers are explored as a new system for controlled drug delivery.
Novel techniques capable of obtaining polymer nanofibers have been reported in the literature.
They include solution blow spinning (SBS), which is a technique to produce polymer nanofibers in the same range as electrospinning, using pressurized gas instead of high voltage.
The present study investigates release characteristics of diclofenac sodium encapsulated at three concentrations (5, 10, and 20% w/v) in poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanofibers made by electrospinning and SBS and determines the drug’s effect on fiber morphology and structural properties.
PHBV nanofibers were characterized using scanning electronic microscopy, differential scanning calorimetry, and X-ray diffraction, and the release profile was examined via UV-Vis spectrophotometry.
Both electrospinning and SBS encapsulated diclofenac sodium in PHBV membranes efficiently and effectively.
The profile of the in vitro release of diclofenac sodium was dependent on drug concentration and temperature.
The drug reduced crystallinity and increased flexibility.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Souza, Michelle Andrade& Sakamoto, Karine Yamamura& Mattoso, Luiz H. C.. 2014. Release of the Diclofenac Sodium by Nanofibers of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Obtained from Electrospinning and Solution Blow Spinning. Journal of Nanomaterials،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1041216
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Souza, Michelle Andrade…[et al.]. Release of the Diclofenac Sodium by Nanofibers of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Obtained from Electrospinning and Solution Blow Spinning. Journal of Nanomaterials No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1041216
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Souza, Michelle Andrade& Sakamoto, Karine Yamamura& Mattoso, Luiz H. C.. Release of the Diclofenac Sodium by Nanofibers of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Obtained from Electrospinning and Solution Blow Spinning. Journal of Nanomaterials. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1041216
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1041216
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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