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A Case-Control Study of the Role of Human Papillomavirus in Oesophageal Squamous Cell Carcinoma in Australia
المؤلفون المشاركون
MacIntyre, Chandini Raina
Garland, Suzanne M.
Tabrizi, Sepehr N.
Liyanage, Surabhi S.
Segelov, Eva
Malik, Aisha
Cummins, Eleanor
Moa, Aye
Barbour, Andrew P.
Crowe, Philip J.
Seale, Holly
Rahman, Bayzidur
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-28
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
We investigate the prevalence of human papillomavirus (HPV) in oesophageal squamous cell carcinoma (OSCC) tissues compared to oesophageal tissue from healthy controls, in an Australian cohort.
Methods.
We conducted a hospital-based case-control study of 99 patients with OSCC and 100 healthy controls to examine the presence of HPV DNA.
Paraffin tissues were tested using the PapType high-risk HPV detection and genotyping kit and with INNO-LiPA HPV Genotyping Extra.
The biopsy samples were tested for HPV using a PCR-ELISA method based on the L1 consensus primer set PGMY09-PGMY11.
Results.
HPV DNA of the oncogenic genotype 16 was detected in 1/99 case specimens, a rate of 1010 per 100,000 (95% CI: 30–5500).
All control specimens were negative for HPV.
Significantly higher rates of smoking, other aerodigestive cancers, and mortality were seen among cases than controls.
A pooled analysis of this study and the only other Australian case-control study found that 9/321 cases and 0/155 controls were positive for HPV.
The pooled odds ratio for HPV being a risk factor for OSCC was 9.35 (95% CI: 0.47–190.33).
Conclusion.
Our results suggest that in this multifactorial cancer HPV may be an additional risk factor; although a larger, better powered study is needed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liyanage, Surabhi S.& Segelov, Eva& Malik, Aisha& Garland, Suzanne M.& Tabrizi, Sepehr N.& Cummins, Eleanor…[et al.]. 2014. A Case-Control Study of the Role of Human Papillomavirus in Oesophageal Squamous Cell Carcinoma in Australia. Journal of Oncology،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1042226
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liyanage, Surabhi S.…[et al.]. A Case-Control Study of the Role of Human Papillomavirus in Oesophageal Squamous Cell Carcinoma in Australia. Journal of Oncology No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1042226
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liyanage, Surabhi S.& Segelov, Eva& Malik, Aisha& Garland, Suzanne M.& Tabrizi, Sepehr N.& Cummins, Eleanor…[et al.]. A Case-Control Study of the Role of Human Papillomavirus in Oesophageal Squamous Cell Carcinoma in Australia. Journal of Oncology. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1042226
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1042226
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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